Gastric dumping syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Umar Ahmad, M.D.[2]

Overview

Incidence and prevalence varies depending on the procedure or disease leading to dumping syndrome.

The incidence of patients who have undergone gastric surgery ranges from approximately 20,000 per 100,000 to 50,000 per 100,000.^[1]
Out of these about 1-5% reported severe symptoms.
After truncal vagotomy with drainage the incidence of dumping syndrome has been reported to be 6,000 per 100,000 to 14,000 per 100,000.
After proximal vagotomy without drainage the incidence of dumping syndrome has been reported to be is less than 2,000 per 100,000.
After partial gastrectomy the incidence of dumping syndrome has been reported to be 14,000 per 100,000 to 20,000 per 100,000.
Proximal vagatomy is a fairly newer procedure that leads to lower incidence rates due to the minimized interference in gastric emptying.^[2]

Reductions in the need for elective gastric surgery have led to a decline in the frequency of postgastrectomy syndromes. A 10-fold reduction has occurred in elective operations for peptic ulcer disease in the last 20-30 years. Although this trend preceded the advent of histamine-2 receptor antagonists, these drugs and proton pump inhibitors have accelerated the decline. Helicobacter pylori treatment and eradication in patients with peptic ulcer disease have further decreased the need for surgery.

In 2012, the mortality rate of bariatric surgery leading to dumping syndrome was approximately 1,000 per 100,000 individuals with about 10% having serious complications.^[4]

Patients of all age groups may develop [disease name].
The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
[Disease name] commonly affects individuals younger than/older than [number of years] years of age.
[Chronic disease name] is usually first diagnosed among [age group].
[Acute disease name] commonly affects [age group].

There is no racial predilection to [disease name].
[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].

[Disease name] affects men and women equally.
[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.

[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

↑ Mala T, Hewitt S, Høgestøl IK, Kjellevold K, Kristinsson JA, Risstad H (2015). "[Dumping syndrome following gastric surgery]". Tidsskr. Nor. Laegeforen. (in Norwegian). 135 (2): 137–41. doi:10.4045/tidsskr.14.0550. PMID 25625992.
↑ Mala T, Hewitt S, Høgestøl IK, Kjellevold K, Kristinsson JA, Risstad H (2015). "[Dumping syndrome following gastric surgery]". Tidsskr. Nor. Laegeforen. (in Norwegian). 135 (2): 137–41. doi:10.4045/tidsskr.14.0550. PMID 25625992.
↑ Héraïef R, Giusti V (2014). "[Prevalence of early and late dumping after gastric bypass]". Rev Med Suisse (in French). 10 (423): 696–8, 700. PMID 24783736.
↑ Schneider A, Gottrand F, Sfeir R, Duhamel A, Bonnevalle M, Guimber D, Michaud L (2012). "Postoperative lower esophageal dilation in children following the performance of Nissen fundoplication". Eur J Pediatr Surg. 22 (5): 399–403. doi:10.1055/s-0032-1315807. PMID 22773348.