Gastric dumping syndrome epidemiology and demographics: Difference between revisions

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*Proximal vagatomy is a fairly newer procedure that leads to lower incidence rates due to the minimized interference in gastric emptying.<ref name="pmid256259923">{{cite journal |vauthors=Mala T, Hewitt S, Høgestøl IK, Kjellevold K, Kristinsson JA, Risstad H |title=[Dumping syndrome following gastric surgery] |language=Norwegian |journal=Tidsskr. Nor. Laegeforen. |volume=135 |issue=2 |pages=137–41 |year=2015 |pmid=25625992 |doi=10.4045/tidsskr.14.0550 |url=}}</ref>
*Proximal vagatomy is a fairly newer procedure that leads to lower incidence rates due to the minimized interference in gastric emptying.<ref name="pmid256259923">{{cite journal |vauthors=Mala T, Hewitt S, Høgestøl IK, Kjellevold K, Kristinsson JA, Risstad H |title=[Dumping syndrome following gastric surgery] |language=Norwegian |journal=Tidsskr. Nor. Laegeforen. |volume=135 |issue=2 |pages=137–41 |year=2015 |pmid=25625992 |doi=10.4045/tidsskr.14.0550 |url=}}</ref>


*Reductions in the need for elective gastric surgery have led to a decline in the frequency of postgastrectomy syndromes. A 10-fold reduction has occurred in elective operations for peptic ulcer disease in the last 20-30 years. Although this trend preceded the advent of histamine-2 receptor antagonists, these drugs and proton pump inhibitors have accelerated the decline. Helicobacter pylori treatment and eradication in patients with peptic ulcer disease have further decreased the need for surgery.
*Since the advent of proton pump inhibitors, the need for surgery has decreased and so has the incidence of dumping syndrome.


===Prevalence===
===Prevalence===
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*Approximately 17.5% are affected.
*Approximately 17.5% are affected.


===Case-fatality rate/Mortality rate===
===Mortality rate===
*In 2012, the mortality rate of bariatric surgery leading to dumping syndrome was approximately 1,000  per 100,000 individuals with about 10% having serious complications.<ref name="pmid22773348">{{cite journal |vauthors=Schneider A, Gottrand F, Sfeir R, Duhamel A, Bonnevalle M, Guimber D, Michaud L |title=Postoperative lower esophageal dilation in children following the performance of Nissen fundoplication |journal=Eur J Pediatr Surg |volume=22 |issue=5 |pages=399–403 |year=2012 |pmid=22773348 |doi=10.1055/s-0032-1315807 |url=}}</ref>
*In 2012, the mortality rate of bariatric surgery leading to dumping syndrome was approximately 1,000  per 100,000 individuals with 10% having serious complications.<ref name="pmid22773348">{{cite journal |vauthors=Schneider A, Gottrand F, Sfeir R, Duhamel A, Bonnevalle M, Guimber D, Michaud L |title=Postoperative lower esophageal dilation in children following the performance of Nissen fundoplication |journal=Eur J Pediatr Surg |volume=22 |issue=5 |pages=399–403 |year=2012 |pmid=22773348 |doi=10.1055/s-0032-1315807 |url=}}</ref>


===Age===
=== Age ===
*Patients of all age groups may develop [disease name].
*People aged 45-74 are 2 times more likely to be diagnosed.
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*Children aged less than 1 year old are 3 times less likely to be diagnosed with dumping syndrome.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.  
*Toddlers and preschoolers are are 7 times less likely to be diagnosed with dumping syndrome.  
*[Chronic disease name] is usually first diagnosed among [age group].
*Children aged 5 to 14 years old are 10 times less likely to be diagnosed with dumping syndrome.
*[Acute disease name] commonly affects [age group].
*Elderly people whose ages are over 75 years old are 11 times less likely to be diagnosed with dumping syndrome.
*Teenagers and adults aged 15 to 29 years old are 23 times less likely to be diagnosed with dumping syndrome.


===Race===
===Race===

Revision as of 22:29, 16 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Umar Ahmad, M.D.[2]

Overview

Incidence and prevalence varies depending on the procedure or disease leading to dumping syndrome.

Epidemiology and Demographics

Incidence

  • The incidence of patients who have undergone gastric surgery ranges from approximately 20,000 per 100,000 to 50,000 per 100,000.[1]
  • Out of these about 1-5% reported severe symptoms.
  • After truncal vagotomy with drainage the incidence of dumping syndrome has been reported to be 6,000 per 100,000 to 14,000 per 100,000.
  • After proximal vagotomy without drainage the incidence of dumping syndrome has been reported to be is less than 2,000 per 100,000.
  • After partial gastrectomy the incidence of dumping syndrome has been reported to be 14,000 per 100,000 to 20,000 per 100,000.
  • Proximal vagatomy is a fairly newer procedure that leads to lower incidence rates due to the minimized interference in gastric emptying.[2]
  • Since the advent of proton pump inhibitors, the need for surgery has decreased and so has the incidence of dumping syndrome.

Prevalence

  • Prevalence has not been well studied in gastric dumping syndrome.[3]
  • Approximately 17.5% are affected.

Mortality rate

  • In 2012, the mortality rate of bariatric surgery leading to dumping syndrome was approximately 1,000 per 100,000 individuals with 10% having serious complications.[4]

Age

  • People aged 45-74 are 2 times more likely to be diagnosed.
  • Children aged less than 1 year old are 3 times less likely to be diagnosed with dumping syndrome.
  • Toddlers and preschoolers are are 7 times less likely to be diagnosed with dumping syndrome.
  • Children aged 5 to 14 years old are 10 times less likely to be diagnosed with dumping syndrome.
  • Elderly people whose ages are over 75 years old are 11 times less likely to be diagnosed with dumping syndrome.
  • Teenagers and adults aged 15 to 29 years old are 23 times less likely to be diagnosed with dumping syndrome.

Race

  • There is no racial predilection to [disease name].
  • [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].

Gender

  • [Disease name] affects men and women equally.
  • [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.

Region

  • The majority of [disease name] cases are reported in [geographical region].
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

Developed Countries

References

  1. Mala T, Hewitt S, Høgestøl IK, Kjellevold K, Kristinsson JA, Risstad H (2015). "[Dumping syndrome following gastric surgery]". Tidsskr. Nor. Laegeforen. (in Norwegian). 135 (2): 137–41. doi:10.4045/tidsskr.14.0550. PMID 25625992.
  2. Mala T, Hewitt S, Høgestøl IK, Kjellevold K, Kristinsson JA, Risstad H (2015). "[Dumping syndrome following gastric surgery]". Tidsskr. Nor. Laegeforen. (in Norwegian). 135 (2): 137–41. doi:10.4045/tidsskr.14.0550. PMID 25625992.
  3. Héraïef R, Giusti V (2014). "[Prevalence of early and late dumping after gastric bypass]". Rev Med Suisse (in French). 10 (423): 696–8, 700. PMID 24783736.
  4. Schneider A, Gottrand F, Sfeir R, Duhamel A, Bonnevalle M, Guimber D, Michaud L (2012). "Postoperative lower esophageal dilation in children following the performance of Nissen fundoplication". Eur J Pediatr Surg. 22 (5): 399–403. doi:10.1055/s-0032-1315807. PMID 22773348.

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