Gangrene

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Gangrene
Diabetic with severe infection and loss of toes - wet gangrene in center.

Gangrene Microchapters

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Overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]




Etymology

The etymology of gangrene derives from the Latin word "gangraena" and from the Greek gangraina (γάγγραινα), which means "putrefaction of tissues".


Treatment

As early as 1028, when antibiotics had not yet been discovered, fly maggots were commonly used to treat chronic wounds or ulcers to prevent or arrest necrotic spread, as some species of maggots consume only dead flesh, leaving nearby living tissue unaffected. This practice largely died out after the introduction of antibiotics and enzyme to the range of treatments for wounds. Recently, however, maggot therapy has regained some credibility and is sometimes employed with great efficacy in cases of chronic tissue necrosis.

In modern times treatment is usually surgical debridement, and excision with amputation is necessary in many cases. Antibiotics alone are not effective because they do not penetrate ischemic muscles sufficiently.

See also

References

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ar:غنغرينة bg:Гангрена ca:Gangrena cs:Gangréna da:Gangræn de:Gangrän et:Gangreen eo:Gangreno fa:قانقاریا io:Gangreno is:Kolbrandur it:Cancrena he:נמק nl:Gangreen no:Koldbrann qu:Kawsaykuq tantalli ismusqa scn:Cancrena fi:Kuolio sv:Kallbrand uk:Гангрена wa:Grangrin




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