Ganglioglioma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

On MRI of the brain, ganglioglioma is characterized by iso- to hypointense solid component on T1, variable contrast enhancement of solid component on T1 C+ (Gd), hyperintense solid component and variable signal in cystic component on T2, and calcification on T2 (GE/SWI).[1] On MRI of the spinal cord, ganglioglioma is characterized by mixed signal intensity on T1-weighted images, high intensity on T2, patchy enhancement on T1 C+ (Gd), and calcification with low signal blooming on gradient echo.

MRI

  • 1. Brain MRI scan is helpful in the diagnosis of cerebral ganglioglioma. On MRI of the brain, ganglioglioma is characterized by:[1]
MRI Component Features
T1​
  • Solid component iso- to hypointense
T1 C+ (Gd)
  • Solid component variable contrast enhancement
T2
  • Hyperintense solid component
  • Variable signal in the cystic component
  • Peritumoral flair/T2 edema is rare
T2 (GE/SWI)
  • Calcified areas shows blooming signal loss
  • 2. MRI scan of the spinal cord is helpful in the diagnosis of spinal cord ganglioglioma. On MRI of the spinal cord, ganglioglioma is characterized by:[2]
MRI Component Features
T1​
  • Mixed signal intensity
T1 C+ (Gd)
  • Patchy or no enhancement
T2
  • High intensity
  • Surrounding edema is rare
Gradient echo

References

  1. 1.0 1.1 MRI findings of ganglioglioma. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioglioma
  2. Imaging findings of spinal cord ganglioglioma. Dr Ayush Goel and Dr Sara Wein et al. http://radiopaedia.org/articles/spinal-ganglioglioma


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