Ganglioglioma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]

Overview

MRI

Brain MRI may be helpful in the diagnosis of ganglioglioma.

  • In MRI imaging, ganglioglioma may appear as solid or cystic lesions.
  • MRI T1-weighted images show a hypointense mass.
  • MRI T2-weighted and FLAIR images show a well-circumscribed hyperintense mass.
  • Ganglioglioma often does not enhance with intravenous gadolinium. However, some tumors have mild diffuse or patchy enhancement without ring appearance.
  • Conventionally they are sharply demarcated, but some are infiltrative and are indistinguishable from diffuse gliomas.
  • Anaplastic ganglioglioma is frequently infiltrative on MRI and is associated with a higher degree of gadolinium enhancement.
  • Overall, diagnosis might be suggested by clinical presentation and MRI characteristics, but the definitive diagnosis is only made by histopathological examination of the tumor. Review : [1] [2] [3]

References

  1. Soffietti R, Rudà R, Reardon D (2016). "Rare glial tumors". Handb Clin Neurol. 134: 399–415. doi:10.1016/B978-0-12-802997-8.00024-4. PMID 26948368.
  2. Hayat, M. A. (2012). Tumors of the central nervous system. Dordrecht New York: Springer. ISBN 978-94-007-5487-4.
  3. Raizer, Jeffrey J.; Naidich, Michelle J. (2008). "Neuronal Tumors": 435–448. doi:10.1016/B978-012370863-2.50045-2.


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