Ganglioglioma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

On MRI brain, ganglioglioma is characterized by iso- to hypointense solid component on T1, variable contrast enhancement of solid component on T1 C+ (Gd), hyperintense solid component and variable signal in cystic component on T2, and calcification on T2 (GE/SWI).[1] On MRI scan of spinal cord, ganglioglioma is characterized by mixed signal intensity on T1-weighted images, high intensity on T2, patchy enhancement on T1 C+ (Gd), and calcification with low signal blooming on gradient echo.[2]

MRI

1. Brain MRI scan is helpful in the diagnosis of cerebral ganglioglioma. On MRI brain, it is characterized by:[1]

T1

  • Solid component iso- to hypointense

T1 C+ (Gd)

  • Solid component variable contrast enhancement

T2

  • Hyperintense solid component
  • Variable signal in the cystic component (depending on amount of proteinaceous material or presence of blood products)
  • Peritumoral FLAIR/T2 edema is rare

T2 (GE/SWI)

  • Calcified areas shows blooming signal loss

2. MRI scan of spinal cord is helpful in the diagnosis of spinal cord ganglioglioma. On MRI scan of spinal cord, it is characterized by:[2]

T1

  • Mixed signal intensity on T1-weighted images is due to the dual cellular elements of the tumor

T2

  • High intensity
  • Surrounding edema is rare

T1 C+ (Gd)

  • Patchy enhancement

Gradient echo

  • Calcification is common, low signal with blooming

References

  1. 1.0 1.1 MRI findings of ganglioglioma. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioglioma
  2. 2.0 2.1 MRI findings of spinal cord ganglioglioma. Dr Ayush Goel and Dr Sara Wein et al. Radiopaedia 2015. http://radiopaedia.org/articles/spinal-ganglioglioma


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