Ganglioglioma MRI: Difference between revisions

Jump to navigation Jump to search
 
(11 intermediate revisions by 4 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Ganglioglioma}}
{{Ganglioglioma}}
{{CMG}}{{AE}}{{SR}}
{{CMG}}{{AE}}{{MC}}


==Overview==
==Overview==
On MRI of the brain, ganglioglioma is characterized by iso- to hypointense solid component on T1, variable contrast enhancement of solid component on T1 C+ (Gd), hyperintense solid component and variable signal in cystic component on T2, and [[calcification]] on T2 (GE/SWI).<ref name=dd>MRI findings of ganglioglioma. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioglioma</ref> On MRI scan of [[spinal cord]], ganglioglioma is characterized by mixed signal intensity on T1-weighted images, high intensity on T2, patchy enhancement on T1 C+ (Gd), and [[calcification]] with low signal blooming on gradient echo.<ref name=cc>MRI findings of spinal cord ganglioglioma. Dr Ayush Goel and Dr Sara Wein et al. Radiopaedia 2015. http://radiopaedia.org/articles/spinal-ganglioglioma</ref>


==MRI==
==MRI==
*'''''1. Brain MRI scan is helpful in the diagnosis of cerebral ganglioglioma. On MRI of the brain, it is characterized by:'''''<ref name=dd>MRI findings of ganglioglioma. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioglioma</ref>
Brain MRI may be helpful in the diagnosis of ganglioglioma.  
 
* In MRI imaging, ganglioglioma may appear as solid or cystic lesions.
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
* MRI T1-weighted images show a hypointense mass.
|valign=top|
* MRI T2-weighted and FLAIR images show a well-circumscribed hyperintense mass.
|+
* Ganglioglioma often does not enhance with intravenous gadolinium. However, some tumors have mild diffuse or patchy enhancement without ring appearance.
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|MRI Component}}
* Conventionally they are sharply demarcated, but some are infiltrative and are indistinguishable from diffuse gliomas.
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Features}}
* Anaplastic ganglioglioma is frequently infiltrative on MRI and is associated with a higher degree of gadolinium enhancement.
|-
* Overall, diagnosis might be suggested by clinical presentation and MRI characteristics, but the definitive diagnosis is only made by histopathological examination of the tumor. Review : <ref name="pmid26948368">{{cite journal| author=Soffietti R, Rudà R, Reardon D| title=Rare glial tumors. | journal=Handb Clin Neurol | year= 2016 | volume= 134 | issue=  | pages= 399-415 | pmid=26948368 | doi=10.1016/B978-0-12-802997-8.00024-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26948368  }} </ref> <ref name="">{{cite book | last = Hayat | first = M. A. | title = Tumors of the central nervous system | publisher = Springer | location = Dordrecht New York | year = 2012 | isbn = 978-94-007-5487-4 }}</ref> <ref name="RaizerNaidich2008">{{cite journal|last1=Raizer|first1=Jeffrey J.|last2=Naidich|first2=Michelle J.|title=Neuronal Tumors|year=2008|pages=435–448|doi=10.1016/B978-012370863-2.50045-2}}</ref>
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
:T1​
| style="padding: 5px 5px; background: #F5F5F5;" |
*Solid component iso- to hypointense
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:T1 C+ (Gd)
| style="padding: 5px 5px; background: #F5F5F5;" |
*Solid component variable contrast enhancement
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:T2
| style="padding: 5px 5px; background: #F5F5F5;" |
*Hyperintense solid component
*Variable signal in the cystic component
*Peritumoral flair/T2 edema is rare
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:T2 (GE/SWI)
| style="padding: 5px 5px; background: #F5F5F5;" |
*Calcified areas shows blooming signal loss
|}
 
*'''''2. MRI scan of the [[spinal cord]] is helpful in the diagnosis of spinal cord ganglioglioma. On MRI of the spinal cord, it is characterized by:'''''<ref name=ddd> Imaging findings of spinal cord ganglioglioma. http://radiopaedia.org/articles/spinal-ganglioglioma</ref>
 
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
|valign=top|
|+
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|MRI Component
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Features}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
:T1​
| style="padding: 5px 5px; background: #F5F5F5;" |
*Mixed signal intensity
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:T1 C+ (Gd)
| style="padding: 5px 5px; background: #F5F5F5;" |
*Patchy or no enhancement
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:T2
| style="padding: 5px 5px; background: #F5F5F5;" |
*High intensity
*Surrounding [[edema]] is rare
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Gradient echo
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Calcification]] is common, low signal with blooming
|}


==References==
==References==
Line 77: Line 24:
{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Neurology]]
[[Category:Neurosurgery]]

Latest revision as of 20:35, 2 August 2019

Ganglioglioma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Risk Factors

Screening

Differentiating Ganglioglioma from other Diseases

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Ganglioglioma MRI On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Ganglioglioma MRI

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA onGanglioglioma MRI

CDC on Ganglioglioma MRI

Ganglioglioma MRI in the news

on Ganglioglioma MRI

Directions to Hospitals Treating Ganglioglioma

Risk calculators and risk factors for Ganglioglioma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]

Overview

MRI

Brain MRI may be helpful in the diagnosis of ganglioglioma.

  • In MRI imaging, ganglioglioma may appear as solid or cystic lesions.
  • MRI T1-weighted images show a hypointense mass.
  • MRI T2-weighted and FLAIR images show a well-circumscribed hyperintense mass.
  • Ganglioglioma often does not enhance with intravenous gadolinium. However, some tumors have mild diffuse or patchy enhancement without ring appearance.
  • Conventionally they are sharply demarcated, but some are infiltrative and are indistinguishable from diffuse gliomas.
  • Anaplastic ganglioglioma is frequently infiltrative on MRI and is associated with a higher degree of gadolinium enhancement.
  • Overall, diagnosis might be suggested by clinical presentation and MRI characteristics, but the definitive diagnosis is only made by histopathological examination of the tumor. Review : [1] [2] [3]

References

  1. Soffietti R, Rudà R, Reardon D (2016). "Rare glial tumors". Handb Clin Neurol. 134: 399–415. doi:10.1016/B978-0-12-802997-8.00024-4. PMID 26948368.
  2. Hayat, M. A. (2012). Tumors of the central nervous system. Dordrecht New York: Springer. ISBN 978-94-007-5487-4.
  3. Raizer, Jeffrey J.; Naidich, Michelle J. (2008). "Neuronal Tumors": 435–448. doi:10.1016/B978-012370863-2.50045-2.


Template:WikiDoc Sources