Fungal meningitis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]

Overview

Historical perspective

The major advancements in the history of meningitis may be summarized as follows:[1] [2]

  • C. neoformans, an encapsulated basidiomycetous yeast, represents one of the most common CNS pathogens encountered in clinical practice today.
  • The first report of human cryptococcosis was published by Busse and Busckhe more than 100 years ago; 10 years later, it was identified as the cause of human meningitis.
  • In 1661, Thomas Willis first described the inflammation of meninges and an epidemic of meningitis.
  • In 1891, Heinrich Quincke provided an early analysis of CSF by introducing a new technique of lumbar puncture.
  • In early 19th century, detailed profile of CSF analysis in meningitis was explained by William Mestrezat, and H. Houston Merritt.
  • Advancements regarding the treatment of bacterial meningitis was given by Georg Joachmann in Germany and Simon Flexnor in USA in 18th and 19th century respectively

References

  1. Tyler KL (2010). "Chapter 28: a history of bacterial meningitis". Handb Clin Neurol. 95: 417–33. doi:10.1016/S0072-9752(08)02128-3. PMID 19892131.
  2. Fungal Meningitis, Infections of the Central Nervous System Author: Horan ; Perfect, Jennifer, John L. R. Identifier: ISBN: 978-1-4698-8366-3 Part VI chapter 40

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