Fibroadenoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Fibroadenoma may be classified according to microscopic histopathological analysis into four subtypes, which include juvenile fibroadenoma, complex fibroadenoma, myxoid fibroadenoma, and cellular fibroadenoma.

Classification

• Fibroadenoma may be classified according to microscopic histopathological analysis into four subtypes, which include:

• Juvenile fibroadenoma
• Complex fibroadenoma
• Myxoid fibroadenoma
• Cellular fibroadenoma

• The table below differentiates between the four main subtypes of fibrodenoma according to microscopic histopathological analysis:

Fibroadenoma Subtype	Description
Juvenile fibroadenoma	Stromal and epithelial hyperplasia Tapering, thin micropapillae (gynecomastoid hyperplasia) Mitoses is absent
Complex fibroadenoma	Excessive proliferation of epithelial cells Apocrine metaplasia Cysts > 3 mm Calcification Sclerosing adenosis
Myxoid fibroadenoma	Myxoid stroma
Cellular fibroadenoma	Relatively high cellular component Increased mitotic rate Absence of calcification and sclerosing adenosis