Fever of unknown origin laboratory findings

Jump to navigation Jump to search
Resident
Survival
Guide

Fever of unknown origin Microchapters

Home

Patient Information

Overview

Historical perspective

Pathophysiology

Causes

Differentiating Fever of unknown origin from other Diseases

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and ultrasound

CT scan

MRI

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Fever of unknown origin laboratory findings On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Fever of unknown origin laboratory findings

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Fever of unknown origin laboratory findings

CDC on Fever of unknown origin laboratory findings

Fever of unknown origin laboratory findings in the news

Blogs on Fever of unknown origin laboratory findings

Directions to Hospitals Treating Fever of unknown origin

Risk calculators and risk factors for Fever of unknown origin laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; fever/pyrexia of obscured/undetermined/uncertain/unidentifiable/unknown focus/origin/source; fever/pyrexia without a focus/origin/source; FUO; PUO

Overview

A comprehensive and meticulous history (i.e. illness of family members, recent visit to the tropics, medication), repeated physical examination (i.e. skin rash, eschar, lymphadenopathy, heart murmur) and a myriad of laboratory tests (serological, blood culture, immunological) are the cornerstone of finding the cause.

Laboratory Findings

Initial laboratory studies in patients with FUO

  • Complete blood count with differential
  • Basic metabolic panel
  • Liver function test including AST, ALT, LDH, bilirubin, alkaline phosphatase
  • Creatine kinase
  • Blood cultures (at least 2 sets)
  • Urinalysis with microscopic examination
  • Urine cultures
  • Erythrocyte sedimentation rate
  • C-reactive protein
  • Gamma-glutamyl transferase
  • Coombs test
  • Cold agglutinins
  • Ferritin
  • Angiotensin-converting enzyme
  • Thyroid peroxidase and anti-thyroglobulin antibodies
  • Antinuclear antibodies
  • Rheumatoid factor
  • Cryoglobulins
  • CMV IgM antibodies and heterophile antibody test if positive for atypical lymphocytes
  • Q fever antibodies for patients with exposure to livestocks
  • HIV antibody
  • Serum protein electrophoresis
  • Tuberculin skin test
  • Fecal occult blood test

References