Extranodal NK-T-cell lymphoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]

Overview


Epidemiology and Demographics

Incidence

  • Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.
  • Nk cell lymphoma is usually associated with Epstein-Barr virus infection.
  • NK T cell lymphoma, nasal type consist 3-10% of non-Hodgkin lymphoma in Asia and South America and less than 1% in Western countries.[1]

Mortality rate

  • NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.

References

  1. Liu J, Song B, Fan T, Huang C, Xie C, Li J; et al. (2011). "Pathological and clinical characteristics of 1,248 non-Hodgkin's lymphomas from a regional cancer hospital in Shandong, China". Asian Pac J Cancer Prev. 12 (11): 3055–61. PMID 22393989.