Eczema natural history, complications and prognosis: Difference between revisions

Jump to navigation Jump to search
Line 15: Line 15:


=== Comorbidities ===
=== Comorbidities ===
* [[Individuals]] suffering from [[eczema]] often have comorbidities like [[asthma]] <ref> Holgate ST. The epithelium takes centre stage in asthma and atopic dermatitis. Trends Immunol. 2007;28(6):248-251. doi:10.1016/j.it.2007.04.007</ref>, [[allergic rhinitis]] <ref> Zheng T, Yu J, Oh MH, Zhu Z. The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma. Allergy Asthma Immunol Res. 2011;3(2):67-73. doi:10.4168/aair.2011.3.2.67</ref>, [[contact dermatitis]] <ref> de Groot AC. The frequency of contact allergy in atopic patients with dermatitis. Contact Dermatitis. 1990;22(5):273-277. doi:10.1111/j.1600-0536.1990.tb01595.x </ref>, and [[food allergy]] <ref name="pmidhttps://doi.org/10.1016/S0140-6736(81)92459-4">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=https://doi.org/10.1016/S0140-6736(81)92459-4 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10 }} </ref>.
* [[Individuals]] suffering from [[eczema]] often have comorbidities like [[asthma]] <ref name="pmid17466594">{{cite journal| author=Holgate ST| title=The epithelium takes centre stage in asthma and atopic dermatitis. | journal=Trends Immunol | year= 2007 | volume= 28 | issue= 6 | pages= 248-51 | pmid=17466594 | doi=10.1016/j.it.2007.04.007 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17466594  }} </ref>, [[allergic rhinitis]] <ref name="pmid21461244">{{cite journal| author=Zheng T, Yu J, Oh MH, Zhu Z| title=The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma. | journal=Allergy Asthma Immunol Res | year= 2011 | volume= 3 | issue= 2 | pages= 67-73 | pmid=21461244 | doi=10.4168/aair.2011.3.2.67 | pmc=3062798 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21461244  }} </ref>, [[contact dermatitis]] <ref name="pmid2383986">{{cite journal| author=de Groot AC| title=The frequency of contact allergy in atopic patients with dermatitis. | journal=Contact Dermatitis | year= 1990 | volume= 22 | issue= 5 | pages= 273-7 | pmid=2383986 | doi=10.1111/j.1600-0536.1990.tb01595.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2383986  }} </ref>, and [[food allergy]] <ref name="pmid6112605">{{cite journal| author=Jackson PG, Lessof MH, Baker RW, Ferrett J, MacDonald DM| title=Intestinal permeability in patients with eczema and food allergy. | journal=Lancet | year= 1981 | volume= 1 | issue= 8233 | pages= 1285-6 | pmid=6112605 | doi=10.1016/s0140-6736(81)92459-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6112605 }} </ref>
** [[Peanut allergy]] is the most common form of [[food allergy]] associated with [[eczema]]. <ref> Jackson PG, Lessof MH, Baker RW, Ferrett J, MacDonald DM. Intestinal permeability in patients with eczema and food allergy. Lancet. 1981;1(8233):1285-1286. doi:10.1016/s0140-6736(81)92459-4 </ref>
** [[Peanut allergy]] is the most common form of [[food allergy]] associated with [[eczema]]. <ref name="pmid6112605">{{cite journal| author=Jackson PG, Lessof MH, Baker RW, Ferrett J, MacDonald DM| title=Intestinal permeability in patients with eczema and food allergy. | journal=Lancet | year= 1981 | volume= 1 | issue= 8233 | pages= 1285-6 | pmid=6112605 | doi=10.1016/s0140-6736(81)92459-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6112605  }} </ref>
**The National Institute of [[Allergy]] and [[Infectious Diseases]] 2017 guidelines recommend that all [[infants]] suffering from severe [[eczema]] should undergo [[skin prick testing]] or peanut-specific [[IgE]] evaluation to assess for possible occurrence of [[peanut allergy]] and be prevented as early as possible. <ref> Togias A, Cooper SF, Acebal ML, et al. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. J Allergy Clin Immunol. 2017;139(1):29-44. doi:10.1016/j.jaci.2016.10.010</ref>
**The National Institute of [[Allergy]] and [[Infectious Diseases]] 2017 guidelines recommend that all [[infants]] suffering from severe [[eczema]] should undergo [[skin prick testing]] or peanut-specific [[IgE]] evaluation to assess for possible occurrence of [[peanut allergy]] and be prevented as early as possible. <ref name="pmid28137368">{{cite journal| author=Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR, Beck LA | display-authors=etal| title=Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. | journal=J Pediatr Nurs | year= 2017 | volume= 32 | issue=  | pages= 91-98 | pmid=28137368 | doi=10.1016/j.pedn.2016.12.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28137368  }} </ref>
* [[Eczema]] is also associated with [[metabolic]] problems such as [[obesity]]. <ref> Silverberg JI, Kleiman E, Lev-Tov H, et al. Association between obesity and atopic dermatitis in childhood: a case-control study. J Allergy Clin Immunol. 2011;127(5):1180-6.e1. doi:10.1016/j.jaci.2011.01.063 </ref>
* [[Eczema]] is also associated with [[metabolic]] problems such as [[obesity]]. <ref name="pmid21411132">{{cite journal| author=Silverberg JI, Kleiman E, Lev-Tov H, Silverberg NB, Durkin HG, Joks R | display-authors=etal| title=Association between obesity and atopic dermatitis in childhood: a case-control study. | journal=J Allergy Clin Immunol | year= 2011 | volume= 127 | issue= 5 | pages= 1180-6.e1 | pmid=21411132 | doi=10.1016/j.jaci.2011.01.063 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21411132  }} </ref>


=== Complications ===
=== Complications ===

Revision as of 18:23, 10 June 2022

Eczema Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Eczema from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Social Impact

Future or Investigational Therapies

Case Studies

Case #1

Eczema On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Eczema

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Eczema

CDC on Eczema

Eczema in the news

Blogs on Eczema

Directions to Hospitals Treating Eczema

Risk calculators and risk factors for Eczema

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.


Overview

Eczema has regarded as a medical condition with a natural history that occurs consistently. It is characterized as a disease with an early onset, mostly during the childhood period, and remits during the adolescence period. If eczema is left untreated, it can lead to viral, bacterial and fungal infections. Psychological problems could also arise brought about by constant itching.

Eczema Natural History, Complications, and Prognosis

Natural History

  • Eczema has regarded as a medical condition with a natural history that occurs consistently.
  • It is characterized as a disease with an early onset, mostly during the childhood period, and remits during the adolescence period. [1]

Comorbidities

Complications

Prognosis

References

  1. Paternoster L, Savenije OEM, Heron J, Evans DM, Vonk JM, Brunekreef B; et al. (2018). "Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohorts". J Allergy Clin Immunol. 141 (3): 964–971. doi:10.1016/j.jaci.2017.09.044. PMC 5840507. PMID 29129583.
  2. Holgate ST (2007). "The epithelium takes centre stage in asthma and atopic dermatitis". Trends Immunol. 28 (6): 248–51. doi:10.1016/j.it.2007.04.007. PMID 17466594.
  3. Zheng T, Yu J, Oh MH, Zhu Z (2011). "The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma". Allergy Asthma Immunol Res. 3 (2): 67–73. doi:10.4168/aair.2011.3.2.67. PMC 3062798. PMID 21461244.
  4. de Groot AC (1990). "The frequency of contact allergy in atopic patients with dermatitis". Contact Dermatitis. 22 (5): 273–7. doi:10.1111/j.1600-0536.1990.tb01595.x. PMID 2383986.
  5. 5.0 5.1 Jackson PG, Lessof MH, Baker RW, Ferrett J, MacDonald DM (1981). "Intestinal permeability in patients with eczema and food allergy". Lancet. 1 (8233): 1285–6. doi:10.1016/s0140-6736(81)92459-4. PMID 6112605.
  6. Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR, Beck LA; et al. (2017). "Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel". J Pediatr Nurs. 32: 91–98. doi:10.1016/j.pedn.2016.12.006. PMID 28137368.
  7. Silverberg JI, Kleiman E, Lev-Tov H, Silverberg NB, Durkin HG, Joks R; et al. (2011). "Association between obesity and atopic dermatitis in childhood: a case-control study". J Allergy Clin Immunol. 127 (5): 1180–6.e1. doi:10.1016/j.jaci.2011.01.063. PMID 21411132.
  8. Yaghmaie P, Koudelka CW, Simpson EL. Mental health comorbidity in patients with atopic dermatitis. J Allergy Clin Immunol. 2013;131(2):428-433. doi:10.1016/j.jaci.2012.10.041
  9. Buske-Kirschbaum A, Schmitt J, Plessow F, Romanos M, Weidinger S, Roessner V. Psychoendocrine and psychoneuroimmunological mechanisms in the comorbidity of atopic eczema and attention deficit/hyperactivity disorder. Psychoneuroendocrinology. 2013;38(1):12-23. doi:10.1016/j.psyneuen.2012.09.017
  10. Nicholas MN, Gooderham MJ. Atopic Dermatitis, Depression, and Suicidality. J Cutan Med Surg. 2017;21(3):237-242. doi:10.1177/1203475416685078
  11. Meding B, Wrangsjö K, Järvholm B (2005). "Fifteen-year follow-up of hand eczema: persistence and consequences". Br J Dermatol. 152 (5): 975–80. doi:10.1111/j.1365-2133.2005.06494.x. PMID 15888155.
  12. Olesen CM, Agner T, Ebbehøj NE, Carøe TK (2019). "Factors influencing prognosis for occupational hand eczema: new trends". Br J Dermatol. 181 (6): 1280–1286. doi:10.1111/bjd.17870. PMID 30851194.