EIF3H: Difference between revisions

Jump to navigation Jump to search
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS (v470))
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Eukaryotic translation initiation factor 3 subunit H''' is a [[protein]] that in humans is encoded by the ''EIF3H'' [[gene]].<ref name="pmid9341143">{{cite journal | vauthors = Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW | title = Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly | journal = J. Biol. Chem. | volume = 272 | issue = 43 | pages = 27042–52  | date = Nov 1997 | pmid = 9341143 | pmc =  | doi = 10.1074/jbc.272.43.27042 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8667| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa
| HGNCid = 3273
| Symbol = EIF3S3
| AltSymbols =; MGC102958; eIF3-gamma; eIF3-p40; eIF3h
| OMIM = 603912
| ECnumber = 
| Homologene = 2785
| MGIid = 1915385
| GeneAtlas_image1 = PBB_GE_EIF3S3_201592_at_tn.png
| GeneAtlas_image2 = PBB_GE_EIF3S3_gnf1h09511_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003743 |text = translation initiation factor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005852 |text = eukaryotic translation initiation factor 3 complex}}
| Process = {{GNF_GO|id=GO:0006412 |text = translation}} {{GNF_GO|id=GO:0006446 |text = regulation of translational initiation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8667
    | Hs_Ensembl = ENSG00000147677
    | Hs_RefseqProtein = NP_003747
    | Hs_RefseqmRNA = NM_003756
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 8
    | Hs_GenLoc_start = 117726253
    | Hs_GenLoc_end = 117847675
    | Hs_Uniprot = O15372
    | Mm_EntrezGene = 68135
    | Mm_Ensembl = ENSMUSG00000022312
    | Mm_RefseqmRNA = NM_080635
    | Mm_RefseqProtein = NP_542366
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 15
    | Mm_GenLoc_start = 51616634
    | Mm_GenLoc_end = 51695557
    | Mm_Uniprot = Q3THW7
  }}
}}
'''Eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa''', also known as '''EIF3S3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8667| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box BotSee Template:PBB_Controls to Stop updates. -->
EIF3H has been shown to [[Protein-protein interaction|interact]] with [[EIF3A]].<ref name=pmid17353931>{{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Mol. Syst. Biol. | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}</ref><ref name=pmid14519125>{{cite journal | vauthors = Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW | title = Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3 | journal = Eur. J. Biochem. | volume = 270 | issue = 20 | pages = 4133–9 | date = Oct 2003 | pmid = 14519125 | doi = 10.1046/j.1432-1033.2003.03807.x }}</ref><ref name=pmid9822659>{{cite journal | vauthors = Block KL, Vornlocher HP, Hershey JW | title = Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3 | journal = J. Biol. Chem. | volume = 273 | issue = 48 | pages = 31901–8  | date = Nov 1998 | pmid = 9822659 | doi = 10.1074/jbc.273.48.31901 }}</ref>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== See also ==
{{reflist|2}}
*[[Eukaryotic initiation factor 3|Eukaryotic initiation factor 3 (eIF3)]]
==Further reading==
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1-2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
| citations =
* {{cite journal | vauthors = Asano K, Kinzy TG, Merrick WC, Hershey JW | title = Conservation and diversity of eukaryotic translation initiation factor eIF3 | journal = J. Biol. Chem. | volume = 272 | issue = 2 | pages = 1101–9 | year = 1997 | pmid = 8995409 | doi = 10.1074/jbc.272.2.1101 }}
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
* {{cite journal | vauthors = Méthot N, Rom E, Olsen H, Sonenberg N | title = The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170 | journal = J. Biol. Chem. | volume = 272 | issue = 2 | pages = 1110–6 | year = 1997 | pmid = 8995410 | doi = 10.1074/jbc.272.2.1110 }}
*{{cite journal | author=Asano K, Kinzy TG, Merrick WC, Hershey JW |title=Conservation and diversity of eukaryotic translation initiation factor eIF3. |journal=J. Biol. Chem. |volume=272 |issue= 2 |pages= 1101-9 |year= 1997 |pmid= 8995409 |doi= }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1-2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Méthot N, Rom E, Olsen H, Sonenberg N |title=The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170. |journal=J. Biol. Chem. |volume=272 |issue= 2 |pages= 1110-6 |year= 1997 |pmid= 8995410 |doi= }}
* {{cite journal | vauthors = Block KL, Vornlocher HP, Hershey JW | title = Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3 | journal = J. Biol. Chem. | volume = 273 | issue = 48 | pages = 31901–8 | year = 1998 | pmid = 9822659 | doi = 10.1074/jbc.273.48.31901 }}
*{{cite journal  | author=Asano K, Vornlocher HP, Richter-Cook NJ, ''et al.'' |title=Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly. |journal=J. Biol. Chem. |volume=272 |issue= 43 |pages= 27042-52 |year= 1997 |pmid= 9341143 |doi=  }}
* {{cite journal | vauthors = Saramäki O, Willi N, Bratt O, Gasser TC, Koivisto P, Nupponen NN, Bubendorf L, Visakorpi T | title = Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer | journal = Am. J. Pathol. | volume = 159 | issue = 6 | pages = 2089–94 | year = 2001 | pmid = 11733359 | pmc = 1850612 | doi = 10.1016/S0002-9440(10)63060-X }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
* {{cite journal | vauthors = Morris JA, Kandpal G, Ma L, Austin CP | title = DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation | journal = Hum. Mol. Genet. | volume = 12 | issue = 13 | pages = 1591–608 | year = 2003 | pmid = 12812986 | doi = 10.1093/hmg/ddg162 }}
*{{cite journal | author=Block KL, Vornlocher HP, Hershey JW |title=Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. |journal=J. Biol. Chem. |volume=273 |issue= 48 |pages= 31901-8 |year= 1998 |pmid= 9822659 |doi= }}
* {{cite journal | vauthors = Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW | title = Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3 | journal = Eur. J. Biochem. | volume = 270 | issue = 20 | pages = 4133–9 | year = 2003 | pmid = 14519125 | doi = 10.1046/j.1432-1033.2003.03807.x }}
*{{cite journal | author=Saramäki O, Willi N, Bratt O, ''et al.'' |title=Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer. |journal=Am. J. Pathol. |volume=159 |issue= 6 |pages= 2089-94 |year= 2001 |pmid= 11733359 |doi= }}
* {{cite journal | vauthors = Okamoto H, Yasui K, Zhao C, Arii S, Inazawa J | title = PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas | journal = Hepatology | volume = 38 | issue = 5 | pages = 1242–9 | year = 2003 | pmid = 14578863 | doi = 10.1053/jhep.2003.50457 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Savinainen KJ, Linja MJ, Saramäki OR, Tammela TL, Chang GT, Brinkmann AO, Visakorpi T | title = Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer | journal = Br. J. Cancer | volume = 90 | issue = 5 | pages = 1041–6 | year = 2004 | pmid = 14997205 | pmc = 2409619 | doi = 10.1038/sj.bjc.6601648 }}
*{{cite journal | author=Morris JA, Kandpal G, Ma L, Austin CP |title=DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. |journal=Hum. Mol. Genet. |volume=12 |issue= 13 |pages= 1591-608 |year= 2004 |pmid= 12812986 |doi= }}
* {{cite journal | vauthors = Savinainen KJ, Helenius MA, Lehtonen HJ, Visakorpi T | title = Overexpression of EIF3S3 promotes cancer cell growth | journal = Prostate | volume = 66 | issue = 11 | pages = 1144–50 | year = 2006 | pmid = 16652384 | doi = 10.1002/pros.20452 }}
*{{cite journal | author=Mayeur GL, Fraser CS, Peiretti F, ''et al.'' |title=Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3. |journal=Eur. J. Biochem. |volume=270 |issue= 20 |pages= 4133-9 |year= 2003 |pmid= 14519125 |doi= }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Okamoto H, Yasui K, Zhao C, ''et al.'' |title=PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas. |journal=Hepatology |volume=38 |issue= 5 |pages= 1242-9 |year= 2003 |pmid= 14578863 |doi= 10.1053/jhep.2003.50457 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Savinainen KJ, Linja MJ, Saramäki OR, ''et al.'' |title=Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer. |journal=Br. J. Cancer |volume=90 |issue= 5 |pages= 1041-6 |year= 2004 |pmid= 14997205 |doi= 10.1038/sj.bjc.6601648 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal  | author=Savinainen KJ, Helenius MA, Lehtonen HJ, Visakorpi T |title=Overexpression of EIF3S3 promotes cancer cell growth. |journal=Prostate |volume=66 |issue= 11 |pages= 1144-50 |year= 2006 |pmid= 16652384 |doi= 10.1002/pros.20452 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{Initiation factors}}
{{WikiDoc Sources}}
 
 
{{gene-8-stub}}

Revision as of 02:11, 27 October 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Eukaryotic translation initiation factor 3 subunit H is a protein that in humans is encoded by the EIF3H gene.[1][2]

Interactions

EIF3H has been shown to interact with EIF3A.[3][4][5]

See also

References

  1. Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.
  2. "Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa".
  3. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  4. Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
  5. Block KL, Vornlocher HP, Hershey JW (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659.

Further reading