Drug project tutorial

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

   Mission Statement   

   Tutorial   

WikiDoc Drug Project — Tutorial

Step 0. Formatting Basics

0.1 Pasting as Plain Text

  0.1.1   Pasting as plain text must be done by Ctrl+Shift+V in Windows OS (or Cmd+Shift+Opt+V in Mac OS).

  0.1.2   DO NOT USE CTRL+V (OR CMD+V in Mac OS) TO PASTE.

0.2 Removing Extra Line Spaces

  0.2.1   Phantom line spaces generated during copy-pasting commonly appear between paragraphs and at the top. Remove extra line spaces before moving onto the next page.

0.3 Inserting Images for Tables, Graphs, and Packages

  0.3.1   The width of inserted images should be 600px unless otherwise indicated.

  0.3.2   Use the following wikicode:

{| | [[File:NAMEOFTHEIMAGE01.png|thumb|600px]] |}

Step 1. Selecting Appropriate FDA Package Inserts

1.1 Generic Names, Trade Names, and Formulations

  1.1.1   Check the generic name, trade names, and formulations of the drug from both DailyMed and Drugs@FDA.

  1.1.2   Confirm the presence of Original Packager label of each available formulation (solution/tablet/spray) from DailyMed.

  1.1.3   Select the earliest available Original Packager label. Avoid using Repackager labels.

  1.1.4   Take Clopidogrel as an example:

   Clopidogrel is the generic name.

   Plavix is the trade name.

   The earliest available Original Packager label is this.

   Redirect Plavix to the Clopidogrel main page.

1.2 When More Than One Formuation Exists

  1.2.1   Confirm the presence of Patient Information pages for different formulations on WikiDoc.

  1.2.2   Place Patient Information links for different formulations between {{CMG}} and {{SB}}.

  1.2.3   Refer to Metoprolol as an example of a drug with multiple formulations.

Step 2. Drug Template

2.1 Creating the Drug Template

  2.1.1   Search Template:(generic name of the drug, capitalize the first letter) in the search field. (eg, Template:Clopidogrel)

  2.1.2   Click on Create the page "Template:(generic name of the drug)" on this wiki!   which leads to an empty page.

  2.1.3   Go to Example Drug Template.

  2.1.4   Copy the code from the template and paste it back to the new drug template. Replace XXXXX in the template by the generic name, YYYYY by the title in DailyMed and ZZZZZ (in the code) by the brand name you are using. For example, in the Metoprolol page XXXXX corresponds to Metoprolol, YYYYY corresponds to Lopressor (metoprolol tartrate) tablet and ZZZZZ corresponds to Lopressor.

  2.1.5   When more than brand name exist, both of the brand names should be included in the template. Refer to Metoprolol page for an example.

  2.1.6   DO NOT REPLACE EXAMPLE DRUG TEMPLATE.

2.2 Quality Checking the Drug Template

  2.2.1   Fix any misspelling, punctuation error, or malfunctioning link.

  2.2.2   Make sure that the Warning Black Box in the template is in red.

  2.2.3   Make sure that the list of microchapters is similar to that of the template.

  2.2.4   In case of multiple formulations, the links to chapters should start with the Trade names rather than the generic name.

  2.2.5   Refer to Metoprolol as an example of a drug with multiple formulations.

Step 3. Drug Homepage

3.1 Creating/Amending the Drug Homepage

  3.1.1   Search the generic name of the drug in the search field. You have reached the drug homepage. Make sure that only the first letter of the name of the page is capitalized.

  3.1.2   Go to Example Drug Homepage.

  3.1.3   Copy the code from the example drug homepage and paste it back to the drug homepage.

  3.1.4   Replace XXXXX by the generic name, replace ZZZZZ by the trade name and replace YYYYY by the DailyMed name in the template you've created. If more than one brand name is to be used, include their corresponding DailyMed name under the section FDA Package Insert and make sure to surround them by three equal signs.

  3.1.5   DO NOT REPLACE EXAMPLE DRUG HOMEPAGE.

  3.1.6   Accommodate preexisting contents, if any, to the standard format.

  3.1.7   DO NOT REMOVE WORKS DONE BY PREVIOUS EDITORS.

  3.1.8   Include all trade names in {{SB}} and make proper redirections. Make sure to seperate the brand names by a comma followed by a space. Make sure to capitalize the first letter of each brand name.

  3.1.9   Place Patient Information link between {{CMG}} and {{SB}}. Make sure that the sentences corresponding to {{CMG}}, patient information and {{SB}} are on different lines.

  3.1.10   Visit MedlinePlus, if necessary, to collect data for Patient Information. To create Patient Information page for the drug, use the template Example Drug (patient information).

3.2 The Headings on the Drug Homepage

  3.2.1   The drug homepage should contain the following titles: Overview, Category, FDA Package Insert, Taking Alcohol with XXXXX and References.

  3.2.2   In the Overview section, provide a short description of the drug. It should include the name of the generic drug in the first sentence.

  3.2.3   In the Category section, label the drug appropriately by adding appropriate categories. The categories should match the existing category pages on Wikidoc (except for the category drugs [[Category:Drugs]]). Make sure to separate the different categories by a comma followed by a space. Make sure not to capitalize the words after coma. The categories should be listed in alphabetical order.

  3.2.4   In the Taking Alcohol with XXXXX section:

   Search the term Alcohol in the Package Insert on DailyMed.

   Place the information relating to combined alcohol use under the heading of Taking Alcohol with (Drug).

   If this information is lacking, insert the following statement: Alcohol-(Drug) interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

  3.2.5   In the FDA Package insert section, make sure you include subtitles with the DailyMed names of the brand names of the drug. The subtitles should be surrounded by three equal signs.

  3.2.6   In the Reference section, add the following: {{Reflist|2}} which allows the generation of references into two columns.

3.3 Quality Checking the Drug Homepage

  3.4.1   Headings must be arranged in proper order (Overview, Category, FDA Package Insert, Taking Alcohol with (Drug), and References).

  3.4.2   Apply appropriate categories at the bottom of the page (eg, [[Category:Cardiovascular Drugs]] and [[Category:Drugs]]). Search for the available categories on WikiDoc and try to add all the relevant ones to the page. Always include the category [[Category:Drugs]]. Make sure all the categories are listed in alphabetical order.

  3.4.3   Fix any misspelling, punctuation error, or malfunctioning link.

Step 4. Brand Name Chapters

4.1 Creating the Brand Name Chapters

  4.1.1   Search the brand name of the drug in the search field. You have reached the brand name homepage. Make sure that only the first letter of the name of the page is capitalized.

  4.1.2   Go to Example Brand Name Chapter.

  4.1.3   Copy the code from the example drug homepage and paste it back to a brand name chapter.

  4.1.4   Replace ZZZZZ in the code by the brand name of the drug.

  4.1.5   DO NOT REPLACE EXAMPLE BRAND NAME CHAPTER.

  4.1.6   Apply appropriate categories at the bottom of the page (eg, [[Category:Cardiovascular Drugs]] and [[Category:Drugs]]). Search for the available categories on WikiDoc and try to add all the relevant ones to the page. Always include the category [[Category:Drugs]]. Make sure all the categories are listed in the alphabetical order.

4.2 Quality Checking the Drug Chapters

  4.2.1   Fix any misspelling, punctuation error, or malfunctioning link.

  4.2.2   Make sure all uploaded pictures are appearing.

  4.2.3   Remove extra line spaces and punctuation mistakes at the authorship field of each page.

Step 5. Brand Name Microchapters

5.1 Creating the Brand Name Microchapters

  5.1.1   Click on the name of one of the microchapters from the brand name home page. You have reached a microchapters. Make sure that only the first letter of the title of the page is capitalized.

  5.1.2   Go to Example Brand Name Microchapter.

  5.1.2   Choose the appropriate information from the FDA package insert that fit the title of microchapter (eg: indications), copy it and paste it on the brand name microchapter. Make sure to remove irrelevant content such as numbering.

  5.1.2   If the content of each microchapters can be divided into several parts, choose an appropriate subheading for each part and surround it with 3 equal signs. Make sure that the first letter of each word of the subtitle is capitalized.

  5.1.3   If the copied content contains [see (Section) XX.X], replace it with hyperlink to the corresponding microchapter.

  5.1.4   On the page Label and Packages create subheadings for each type of package label. Under each subheading, retype the information provided on the Label and Packages of the FDA package insert and add the images in the same order of the FDA package insert. Do not take a screenshot of texts but rather type them. Refer to the Lopressor labels and package page as an example.

  5.1.5   Obtain the url of the drug label from DailyMed.

  5.1.6   Create the reference wikicode and paste it back to the drug chapter.

  5.1.7   DO NOT REPLACE EXAMPLE DRUG CHAPTER.

  5.1.8   Apply appropriate categories at the bottom of the page (eg, [[Category:Cardiovascular Drugs]] and [[Category:Drugs]]). Search for the available categories on WikiDoc and try to add all the relevant ones to the page. Always include the category [[Category:Drugs]]. Make sure all the categories are listed in the alphabetical order.

  5.1.9   If the information for certain section is lacking, insert the following statement:

   FDA Package Insert for (Drug) contains no information regarding (Section).

5.2 Black Box Warning

  5.2.1   Boxed warning information must be placed in the Brand name black box warning microchapter.

  5.2.2   Use the following wikicode:

{| style="border: 3px solid #696969;" | style="background: #000000; border: 0px; padding: 20px 20px; width: 800px;" | <center> <font color="#F8F8FF">'''WARNING'''</font> </center> <center> <font color="#F8F8FF" size="1">''See full prescribing information for complete boxed warning.''</font> </center> <b><font color="#F8F8FF"> * Item 1 * Item 2 * Item 2 </font></b> |}

  4.2.3   For instance, boxed warning alert for Toprol XL will appear as:

WARNING See full prescribing information for complete boxed warning. Following abrupt cessation of therapy with beta-blocking agents, exacerbations of angina pectoris and myocardial infarction have occurred. Warn patients against interruption or discontinuation of therapy without the physician’s advice.

5.3 Indications

  5.3.1  In the indications microchapter, make sure to include the following two subheadings surrounded by two equal signs: FDA Labeled Indications and Off Label Indications.

  5.3.2   Under FDA Labeled Indications, copy the content from the FDA label. Make sure that the content is categorized by the different types

  5.3.3   Under Off Label Indications, include the following disclaimer sentence: WikiDoc Drug Project is a constellation of drug information for healthcare providers and patients vigorously vetted on the basis of FDA package insert, MedlinePlus, Practice Guidelines, Scientific Statements, and scholarly medical literature. The information provided is not a medical advice or treatment. WikiDoc does not promote any medication or off-label use of drugs. The disclaimer sentence should be in bold and italic.

  5.3.4   Under Off Label Indications, include a list of indications not approved by the FDA in the following order whenever applicable:

   ====Adult====

   =====Acute=====

   =====Chronic=====

   =====Prophylaxis=====

   ====Pediatrics====

   =====Acute=====

   =====Chronic=====

   =====Prophylaxis=====

  5.3.5   For each of the off label indication, include the dosage, the class and category/level of evidence and the reference.

5.4 Quality Checking the Brand Name Microchapters

  5.4.1   Fix any misspelling, punctuation error, or malfunctioning link.

  5.4.2   Make sure all uploaded pictures are appearing.

  5.4.3   Remove extra line spaces and punctuation mistakes at the authorship field of each page.

  5.4.4   Apply appropriate categories at the bottom of the page (eg, [[Category:Cardiovascular Drugs]] and [[Category:Drugs]]). Search for the available categories on WikiDoc and try to add all the relevant ones to the page. Always include the category [[Category:Drugs]]. Make sure all the categories are listed in the alphabetical order.

Step 6. Completion

5.1 Fix all the errors before announcing the completion.

5.2 Update the status in the progress spreadsheet.

5.3 Submit the page for peer review.