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{{Drug allergy}}
{{Drug allergy}}
==Overview==
==Overview==
 
In general, any allergic reaction will worsen with continued exposure to the offending agent. [[Anaphylaxis]] will most certainly progress to death if untreated, and the same is true for the severe allergic reactions such as [[Stevens-Johnson syndrome]] and [[toxic epidermal necrolysis]].
==Natural History==
==Natural History==
*[[Stevens-Johnson syndrome]] starts with a generalized macropapular rash, that will then progress to bullae, mucous membrane [[ulcerations]], [[conjunctivitis]], [[fever]], [[sore throat]], and [[fatigue]].
*[[Stevens-Johnson syndrome]] starts with a generalized macropapular rash, that will then progress to bullae, mucous membrane [[ulcerations]], [[conjunctivitis]], [[fever]], [[sore throat]], and [[fatigue]].
*[[Toxic epidermal necrolysis]] will progress similarly to [[Stevens-Johnson syndrome]], but will also cause large layers of the [[epidermis]] to detatch from the layers below, leading to extreme amounts of sloughing of the skin surface, and an appearance of the skin that looks like burns or scalding.
*[[Toxic epidermal necrolysis]] will progress similarly to [[Stevens-Johnson syndrome]], but will also cause large layers of the [[epidermis]] to detatch from the layers below, leading to extreme amounts of sloughing of the skin surface, and an appearance of the skin that looks like burns or scalding.
==References==
{{reflist|2}}
[[Category:Allergology]]
[[Category:Immunology]]
[[Category:Emergency medicine]]
[[Category:Needs content]]
{{WH}}
{{WS}}

Latest revision as of 21:41, 13 February 2013

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Overview

In general, any allergic reaction will worsen with continued exposure to the offending agent. Anaphylaxis will most certainly progress to death if untreated, and the same is true for the severe allergic reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis.

Natural History

References

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