Disseminated intravascular coagulation causes: Difference between revisions

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|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Osteomyelitis]]
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| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Antiphospholipid syndrome]], [[meningococcemia|meningococcal septicaemia]], [[neisseria meningiditis]]
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|bgcolor="Beige"| [[Amniotic fluid embolism]], [[Eclampsia]], [[HELLP syndrome]], [[Intrauterine death]], [[Placental abruption]], [[Pre-eclampsia]], [[Retained intrauterine fetal demise]]
|bgcolor="Beige"| [[Amniotic fluid embolism]], [[eclampsia]], [[HELLP syndrome]], [[intrauterine death]], [[pre-eclampsia]], [[Retained intrauterine fetal demise]]
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Revision as of 16:11, 14 February 2014

Disseminated intravascular coagulation Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogheneochuko Ajari, MB.BS, MS [2]

Overview

There are a variety of causes of DIC[1], all usually causing the release of chemicals into the blood that instigates the coagulation.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Disseminated intravascular coagulation in itself is a life-threatening condition and must be treated as such irrespective of the cause.

Common Causes

Causes by Organ System

Cardiovascular Aortic aneurysm, malignant hypertension, myocardial infarction, septic shock, shock, vasculitis
Chemical / poisoning Snake bite (Elapid)
Dermatologic Purpura fulminans, Raynaud's disease, rheumatoid arthritis, vasculitis
Drug Side Effect Amphetamine, cocaine, interleukin 2, serotonin syndrome
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic Acute fatty liver of pregnancy, acute hepatic failure, acute pancreatitis, Crohn disease, fulminant hepatic failure, liver disease, ulcerative colitis
Genetic No underlying causes
Hematologic Acute hemolytic transfusion reactions, acute myeloid leukemia, acute promyelocytic leukemia, antiphospholipid syndrome, Kasabach-Merritt syndrome, myeloproliferative syndrome, paroxysmal nocturnal hemoglobinuria, purpura fulminans, Trousseau's syndrome
Iatrogenic Acute renal allograft rejection, Denver shunt, extensive surgery, LeVeen shunt, liver transplantation, peritoneovenous shunt, prosthetic devices, serotonin syndrome, surgery, recent anesthesia, ventricular assist devices
Infectious Disease Arenaviruses, Argentine hemorrhagic fever, aspergillosis, Bolivian hemorrhagic fever, capnocytophaga canimorsus, CMV, HELLP syndrome, hepatitis viruses, histoplasmosis, malaria (malignant tertian), meningococcal septicaemia, mycoplasma pneumoniae, neisseria meningiditis, osteomyelitis, rocky mountain spotted fever, sarcoidosis, sepsis, septic shock, sleeping sickness (East African), streptococcus pneumoniae, tuberculosis, typhoid fever, viral hemorrhagic fevers, VZV
Musculoskeletal / Ortho Osteomyelitis
Neurologic Antiphospholipid syndrome, meningococcal septicaemia, neisseria meningiditis
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic Amniotic fluid embolism, eclampsia, HELLP syndrome, intrauterine death, pre-eclampsia, Retained intrauterine fetal demise
Oncologic Acute myeloid leukemia, Acute promyelocytic leukemia, Cancers of lung, pancreas, prostate and stomach, Giant hemangioma, Kasabach-Merritt syndrome, Mucin-secreting adenocarcinoma, Myeloproliferative syndromes, Paraneoplastic syndrome, Trousseau's syndrome
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Empyema
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Antiphospholipid syndrome, Macrophage activation syndrome, Raynaud disease, Rheumatoid arthritis
Sexual No underlying causes
Trauma Burns, Crush syndrome, Head injury, Lightning strike, Motor vehicle accidents, Severe tissue injury
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Heat stroke

Causes in Alphabetical Order

References

  1. Ledingham, J (2000). Concise Oxford Textbook of Medicine. Oxford University Press. ISBN 0-19-262870-4, Check |isbn= value: invalid character (help). Unknown parameter |coauthors= ignored (help)
  2. 2.0 2.1 2.2 2.3 2.4 Lurie S, Feinstein M, Mamet Y (2000). "Disseminated intravascular coagulopathy in pregnancy: thorough comprehension of etiology and management reduces obstetricians' stress". Arch Gynecol Obstet. 263 (3): 126–30. PMID 10763841.

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