Coxsackie B4 virus

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Coxsackievirus B4 virus
Coxsackie B4 virus
Coxsackie B4 virus
Virus classification
Group: Group IV ((+)ssRNA)
Family: Picornaviridae
Genus: Enterovirus
Species: Coxsackievirus B4 virus
  • Coxsackie B4 virus is a virus which can trigger an autoimmune reaction which results in destruction of the insulin-producing beta cells of the pancreas, which is one of several different etiologies of diabetes mellitus.
  • An absolute deficiency of insulin renders the person a type 1 diabetic. There are several viruses in the Coxsackie family and many of them seem to evoke this response, as do several other agents. A genetic predisposition appears to be important, such that individuals with HLA types DR3 and DR4 predominate in the affected population.
  • Coxsackie B4 is related to Acute Flaccid Myelitis.[1]

External links

References

  1. Cho SM, MacDonald S, Frontera JA (2017). "Coxsackie B3/B4-Related Acute Flaccid Myelitis". Neurocrit Care. doi:10.1007/s12028-017-0377-8. PMID 28324262.

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