Colon polyps diagnostic study of choice

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Colon polyps Microchapters


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Differentiating Colon polyps from other Diseases

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Diagnostic Study of Choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]


Colonoscopy and flexible sigmoidoscopy are diagnostic studies of choice to diagnose colon polyps.

Diagnostic Study of Choice

Gold standard

  • There are two gold standard tests for the diagnosis of colon polyps include:[1][2][3][4]
    • Colonoscopy
      • Sensitivity of colonoscopy to detect polyps is 85-90%.
      • False negative rate for colonoscopy not to detect polyps of all sizes is 22%. However, false negative rate would be lower if the adenoma is larger.
    • Flexible sigmoidoscopy


  1. Arnesen, R. B.; Ginnerup-Pedersen, B.; Poulsen, P. B.; von Benzon, E.; Adamsen, S.; Laurberg, S.; Hart-Hansen, O. (2016). "Cost-effectiveness of computed tomographic colonography: a prospective comparison with colonoscopy". Acta Radiologica. 48 (3): 259–266. doi:10.1080/02841850601182139. ISSN 0284-1851.
  2. O'Brien, Michael J. (2007). "Hyperplastic and Serrated Polyps of the Colorectum". Gastroenterology Clinics of North America. 36 (4): 947–968. doi:10.1016/j.gtc.2007.08.007. ISSN 0889-8553.
  3. Moreno, Courtney C.; Mittal, Pardeep K.; Henson, Nicholas L.; Baumgarten, Deborah A.; Alexander, Lauren F.; Hanes, Timothy S.; Small, William C.; Kitajima, Hiroumi D.; Kang, Jian; Votaw, John R.; Oshinski, John N.; Dixon, W. Thomas (2014). "Optimal section thickness for detection of polyps at MR: resolution phantom study". Abdominal Imaging. 40 (6): 1451–1456. doi:10.1007/s00261-014-0331-6. ISSN 0942-8925.
  4. Shussman, N.; Wexner, S. D. (2014). "Colorectal polyps and polyposis syndromes". Gastroenterology Report. 2 (1): 1–15. doi:10.1093/gastro/got041. ISSN 2052-0034.

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