Coccidioidomycosis history and symptoms: Difference between revisions

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Latest revision as of 21:00, 29 July 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

A positive history of fever, arthralgia and erythema nodosum are suggestive of coccidioidomycosis. The most common symptoms of coccidioidomycosius include fever with chills, cough, and pleuritic chest pain.^[1]^[2]^[3]^[4]

History

The significant information that needs focus in the history of the patient includes

Any history of travel to the endemic areas
Any ill contact with similar complaints

Symptoms

Clinical manifestations of Coccidioidomycosis range from subclinical infection to fatal disseminated disease. Symptoms are based on the involvement of organ systems: ^[1]^[2]^[3]^[4]

Type of coccidioidomycosis	Symptoms
Pulmonary coccidioidomycosis	Most common symtoms Fever with chills Cough Arthralgia Fatigue Erythema nodosum
Pulmonary coccidioidomycosis	Less common symtoms Weight loss Hemoptysis Night sweats
Disseminated coccidioidomycosis	Its less common for coccidioidomycosis to disseminate, but if occurs symptoms depend on the organ involved Bone: Joint pain , osteomyelitis Skin : Erythema Nodosum, Erythema multiforme CNS : headache, meningitis GI : hepatosplenomegaly Genito-urinary : prostatitis , Testicular swelling

References

↑ ^1.0 ^1.1 Stockamp NW, Thompson GR (2016). "Coccidioidomycosis". Infect. Dis. Clin. North Am. 30 (1): 229–46. doi:10.1016/j.idc.2015.10.008. PMID 26739609.
↑ ^2.0 ^2.1 Twarog M, Thompson GR (2015). "Coccidioidomycosis: Recent Updates". Semin Respir Crit Care Med. 36 (5): 746–55. doi:10.1055/s-0035-1562900. PMID 26398540.
↑ ^3.0 ^3.1 DiCaudo DJ (2014). "Coccidioidomycosis". Semin Cutan Med Surg. 33 (3): 140–5. PMID 25577855.
↑ ^4.0 ^4.1 Malo J, Luraschi-Monjagatta C, Wolk DM, Thompson R, Hage CA, Knox KS (2014). "Update on the diagnosis of pulmonary coccidioidomycosis". Ann Am Thorac Soc. 11 (2): 243–53. doi:10.1513/AnnalsATS.201308-286FR. PMID 24575994.

Template:WH Template:WS

[pmid26739609-1] 1.0 ^1.1 Stockamp NW, Thompson GR (2016). "Coccidioidomycosis". Infect. Dis. Clin. North Am. 30 (1): 229–46. doi:10.1016/j.idc.2015.10.008. PMID 26739609.

[pmid26398540-2] 2.0 ^2.1 Twarog M, Thompson GR (2015). "Coccidioidomycosis: Recent Updates". Semin Respir Crit Care Med. 36 (5): 746–55. doi:10.1055/s-0035-1562900. PMID 26398540.

[pmid25577855-3] 3.0 ^3.1 DiCaudo DJ (2014). "Coccidioidomycosis". Semin Cutan Med Surg. 33 (3): 140–5. PMID 25577855.

[pmid24575994-4] 4.0 ^4.1 Malo J, Luraschi-Monjagatta C, Wolk DM, Thompson R, Hage CA, Knox KS (2014). "Update on the diagnosis of pulmonary coccidioidomycosis". Ann Am Thorac Soc. 11 (2): 243–53. doi:10.1513/AnnalsATS.201308-286FR. PMID 24575994.

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[2]

[3]

[4]

@@ Line 1: / Line 1: @@
 __NOTOC__
-{{CMG}}
 {{Coccidioidomycosis}}
+{{CMG}}; {{AE}}{{ADG}}
+==Overview==
+A positive history of [[fever]], [[arthralgia]] and [[erythema nodosum]] are suggestive of coccidioidomycosis. The most common symptoms of coccidioidomycosius include [[High fever|fever with chills]], [[cough]], and [[pleuritic chest pain]].<ref name="pmid26739609">{{cite journal |vauthors=Stockamp NW, Thompson GR |title=Coccidioidomycosis |journal=Infect. Dis. Clin. North Am. |volume=30 |issue=1 |pages=229–46 |year=2016 |pmid=26739609 |doi=10.1016/j.idc.2015.10.008 |url=}}</ref><ref name="pmid26398540">{{cite journal |vauthors=Twarog M, Thompson GR |title=Coccidioidomycosis: Recent Updates |journal=Semin Respir Crit Care Med |volume=36 |issue=5 |pages=746–55 |year=2015 |pmid=26398540 |doi=10.1055/s-0035-1562900 |url=}}</ref><ref name="pmid25577855">{{cite journal |vauthors=DiCaudo DJ |title=Coccidioidomycosis |journal=Semin Cutan Med Surg |volume=33 |issue=3 |pages=140–5 |year=2014 |pmid=25577855 |doi= |url=}}</ref><ref name="pmid24575994">{{cite journal |vauthors=Malo J, Luraschi-Monjagatta C, Wolk DM, Thompson R, Hage CA, Knox KS |title=Update on the diagnosis of pulmonary coccidioidomycosis |journal=Ann Am Thorac Soc |volume=11 |issue=2 |pages=243–53 |year=2014 |pmid=24575994 |doi=10.1513/AnnalsATS.201308-286FR |url=}}</ref>
-==Symptoms==
+==History==
-{| style="float: right;"
+The significant information that needs  focus in the history of the patient includes
-| [[Image: Valley fever skin lesions.jpg|center|frame|Skin lesion in Valley fever]]
+*Any history of travel to the endemic areas
-|}
+*Any ill contact with similar complaints
+== Symptoms ==
+Clinical manifestations of Coccidioidomycosis range from [[subclinical infection]] to [[Disseminated disease|fatal disseminated disease]]. Symptoms are based on the involvement of organ systems: <ref name="pmid26739609">{{cite journal |vauthors=Stockamp NW, Thompson GR |title=Coccidioidomycosis |journal=Infect. Dis. Clin. North Am. |volume=30 |issue=1 |pages=229–46 |year=2016 |pmid=26739609 |doi=10.1016/j.idc.2015.10.008 |url=}}</ref><ref name="pmid26398540">{{cite journal |vauthors=Twarog M, Thompson GR |title=Coccidioidomycosis: Recent Updates |journal=Semin Respir Crit Care Med |volume=36 |issue=5 |pages=746–55 |year=2015 |pmid=26398540 |doi=10.1055/s-0035-1562900 |url=}}</ref><ref name="pmid25577855">{{cite journal |vauthors=DiCaudo DJ |title=Coccidioidomycosis |journal=Semin Cutan Med Surg |volume=33 |issue=3 |pages=140–5 |year=2014 |pmid=25577855 |doi= |url=}}</ref><ref name="pmid24575994">{{cite journal |vauthors=Malo J, Luraschi-Monjagatta C, Wolk DM, Thompson R, Hage CA, Knox KS |title=Update on the diagnosis of pulmonary coccidioidomycosis |journal=Ann Am Thorac Soc |volume=11 |issue=2 |pages=243–53 |year=2014 |pmid=24575994 |doi=10.1513/AnnalsATS.201308-286FR |url=}}</ref>
+{| class="wikitable"
+!Type of
+coccidioidomycosis
+!Symptoms
+|-
+| rowspan="2" |'''Pulmonary coccidioidomycosis'''
+|<u>'''Most common symtoms'''</u>
+[[Fever|Fever with chills]]
+[[Cough]]
+[[Arthralgia]]
+[[Fatigue]]
+[[Erythema nodosum]]
+|-
+|<u>'''Less common symtoms'''</u>
+[[Weight loss]]
+[[Hemoptysis]]
-Most people infected with the fungi responsible for coccidioidomycosis have minimal to no symptoms. Of those who do develop symptoms, nearly all develop symptoms resembling [[bronchitis]] or [[pneumonia]] that resolve over a matter of a few weeks. Notable coccidioidomycosis signs and symptoms include a profound [[fatigue (medical)|feeling of tiredness]], [[fever]], cough, [[headache]]s, [[rash]], [[myalgia|muscle pain]], and [[arthralgia|joint pain]]. The classic triad of coccidioidomycosis known as "desert rheumatism" includes the combination of fever, joint pains, and [[erythema nodosum]].
+[[Night sweats]]
-Some people do not recover from the initial acute infection and develop a chronic lung infection or widespread disseminated infection (affecting the [[meninges|tissues lining the brain]], soft tissues, joints, and bone). Severe lung disease may develop in [[HIV]]-infected persons.<ref name=Ampel_2005>{{cite journal | author = Ampel N | title = Coccidioidomycosis in persons infected with HIV type 1 | journal = Clin Infect Dis | volume = 41 | issue = 8 | pages = 1174–8 | year = 2005 |pmid = 16163637 | doi = 10.1086/444502}}</ref>
+|-
+|'''Disseminated coccidioidomycosis'''
+|Its less common for coccidioidomycosis to disseminate, but if occurs symptoms depend on the organ involved
+[[Bone|Bone:]] [[Joint pain]] , [[osteomyelitis]]
-Symptoms of coccidioidomycosis include:
+[[Skin]] : [[Erythema nodosum|Erythema Nodosum]], [[Erythema multiforme]]
-* Change in mental status
+[[CNS]] : [[headache]], [[meningitis]]
-* [[Chest pain]] (can vary from mild to severe)
-* [[Cough]], possibly producing blood
-* [[Fever]]
-* [[Headache]]
-* Joint stiffness and pain
-* [[Loss of appetite]]
-* [[Muscle aches]]
-* [[Neck stiffness]]
-* [[Night sweats]]
-* Painful, red lumps on lower legs ([[erythema nodosum]])
-* Sensitivity to light
-* [[Weight loss]]
-* [[Wheezing]]
-Additional symptoms associated with this disease:
+[[Gastrointestinal tract|GI]] : [[hepatosplenomegaly]]
-* Ankle or feet swelling
-* Enlarged or draning lymph nodes
+[[Genitourinary system|Genito-urinary]] : [[prostatitis]] , Testicular swelling
-* [[Joint swelling]]
+|}
 ==References==
 {{Reflist|2}}
+{{WH}}
+{{WS}}
 [[Category:Pulmonology]]
 [[Category:Fungal diseases]]
 [[Category:Biological weapons]]
-[[Category:Infectious disease]]
 [[Category:Disease]]
 [[Category:Needs overview]]
-{{WH}}
+[[Category:Emergency medicine]]
-{{WS}}
+[[Category:Up-To-Date]]
+[[Category:Infectious disease]]