Coccidioidomycosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

A positive history of fever, arthralgia and erythema nodosum are suggestive of coccidioidomycosis. The most common symptoms of coccidioidomycosius include fever with chills, cough, and pleuritic chest pain.[1][2][3][4]

History

The significant information that needs focus in the history of the patient includes

  • Any history of travel to the endemic areas
  • Any ill contact with similar complaints

Symptoms

Clinical manifestations of Coccidioidomycosis range from subclinical infection to fatal disseminated disease. Symptoms are based on the involvement of organ systems: [1][2][3][4]

Type of

coccidioidomycosis

Symptoms
Pulmonary coccidioidomycosis Most common symtoms

Fever with chills

Cough

Arthralgia

Fatigue

Erythema nodosum

Less common symtoms

Weight loss

Hemoptysis

Night sweats

Disseminated coccidioidomycosis Its less common for coccidioidomycosis to disseminate, but if occurs symptoms depend on the organ involved

Bone: Joint pain , osteomyelitis

Skin : Erythema Nodosum, Erythema multiforme

CNS : headache, meningitis

GI : hepatosplenomegaly

Genito-urinary : prostatitis , Testicular swelling

References

  1. 1.0 1.1 Stockamp NW, Thompson GR (2016). "Coccidioidomycosis". Infect. Dis. Clin. North Am. 30 (1): 229–46. doi:10.1016/j.idc.2015.10.008. PMID 26739609.
  2. 2.0 2.1 Twarog M, Thompson GR (2015). "Coccidioidomycosis: Recent Updates". Semin Respir Crit Care Med. 36 (5): 746–55. doi:10.1055/s-0035-1562900. PMID 26398540.
  3. 3.0 3.1 DiCaudo DJ (2014). "Coccidioidomycosis". Semin Cutan Med Surg. 33 (3): 140–5. PMID 25577855.
  4. 4.0 4.1 Malo J, Luraschi-Monjagatta C, Wolk DM, Thompson R, Hage CA, Knox KS (2014). "Update on the diagnosis of pulmonary coccidioidomycosis". Ann Am Thorac Soc. 11 (2): 243–53. doi:10.1513/AnnalsATS.201308-286FR. PMID 24575994.

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