Clopamide: Difference between revisions

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[[Category:Diuretics]]
[[Category:Diuretics]]
[[Category:Thiazides]]
[[Category:Sulfonamides]]
[[Category:Sulfonamides]]
[[Category:Cardiovascular Drugs]]
[[Category:Cardiovascular Drugs]]
[[Category:Drug]]
[[Category:Drug]]

Latest revision as of 19:47, 7 April 2015

Clopamide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC14H20ClN3O3S
Molar mass345.846 g/mol
3D model (JSmol)
  (verify)

WikiDoc Resources for Clopamide

Articles

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Clopamide (trade name Brinaldix) is a piperidine diuretic.

Mechanism of Action

Clopamide is categorised as a thiazide-like diuretic and works in similar way as the thiazide diuretics do. It acts in the kidneys, at the proximal convoluted tubule (PCT) of the nephron where it inhibits the sodium-chloride symporter. Clopamide selectively binds at the chloride binding site of the sodium-chloride symporter in the PCT cells on the luminal (interior) side and thus interferes with the reabsorption of sodium chloride, causing an equiosmolar excretion of water along with sodium chloride.

References