Churg-Strauss syndrome classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]

Overview

According to the American College of Rheumatology (ACR), Eosinophilic granulomatosis with polyangiitis is classified using 6 criteria.

Classification

According to the 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides (DOI 10.1002/art.37715), Eosinophilic granulomatosis with polyangitis (formerly known as Churg-Strauss' syndrome) belongs to the category of ANCA associated vasculitides of the small vessels.

According to the American College of Rheumatology (ACR) Eosinophilic granulomatosis with polyangiitis is classified by 6 criteria. They are:[1]

American College of Rheumatology (ACR) Classification of Eosinophilic granulomatosis with polyangiitis
Asthma
Eosinophilia > 10%
Neuropathy (mononeuropathy or polyneuropathy)
Pulmonary infiltrate, non fixed
Paranasal sinus abnormality
Biopsy that shows extravascular eosinophil infiltration

4 out of the 6 criteria are needed to distinguish Eosinophilic granulomatosis with polyangiitis from other vasculitides.

References

  1. Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP; et al. (1990). "The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis)". Arthritis Rheum. 33 (8): 1094–100. PMID 2202307.

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