Chronic neutrophilic leukemia causes: Difference between revisions
Homa Najafi (talk | contribs) No edit summary |
Homa Najafi (talk | contribs) No edit summary |
||
Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Chronic neutrophilic leukemia}} | {{Chronic neutrophilic leukemia}} | ||
{{CMG}} | {{CMG}} {{AE}}{{Homa}} | ||
==Overview== | ==Overview== | ||
Line 8: | Line 8: | ||
==Etiology== | ==Etiology== | ||
The etiology of CNL is currently unknown. An association between CNL and [[multiple myeloma]] has been suggested based on the observation of myeloma in 20% of CNL cases.<ref name="sta1">[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8098719&query_hl=7&itool=pubmed_ExternalLink] | The etiology of CNL is currently unknown. An association between CNL and [[multiple myeloma]] has been suggested based on the observation of myeloma in 20% of CNL cases.<ref name="sta1">[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8098719&query_hl=7&itool=pubmed_ExternalLink] | ||
Standen GR, Steers FJ, Jones L. "Clonality of chronic neutrophilic | Standen GR, Steers FJ, Jones L. "Clonality of chronic neutrophilic leukemia associated with myeloma: analysis using the X-linked probe M27 beta." '''J Clin Pathol'''. 1993 Apr;46(4):297-8. '''PMID''': 8098719</ref> However, a clonal genetic abnormality has not been detected in these myeloma-associated cases of CNL, raising the possibility that the [[neutrophilia]] is a reaction due to the neoplastic [[myeloma]] cells. The postulated cell of origin is a limited-potential, marrow-derived stem cell.<ref name="yan1">[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9495373&query_hl=10&itool=pubmed_ExternalLink] | ||
Yanagisawa K, Ohminami H, Sato M, Takada K, Hasegawa H, Yasukawa M, Fujita S. "Neoplastic involvement of granulocytic lineage, not granulocytic-monocytic, monocytic, or erythrocytic lineage, in a patient with chronic neutrophilic leukemia." '''Am J Hematol'''. 1998 Mar;57(3):221-4. '''PMID''': 9495373</ref> | Yanagisawa K, Ohminami H, Sato M, Takada K, Hasegawa H, Yasukawa M, Fujita S. "Neoplastic involvement of granulocytic lineage, not granulocytic-monocytic, monocytic, or erythrocytic lineage, in a patient with chronic neutrophilic leukemia." '''Am J Hematol'''. 1998 Mar;57(3):221-4. '''PMID''': 9495373</ref> | ||
Line 19: | Line 19: | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Up-To-Date]] | [[Category:Up-To-Date]] | ||
[[Category:Primary care]] | [[Category:Primary care]] | ||
[[Category:Hematology]] | [[Category:Hematology]] |
Revision as of 14:53, 30 January 2019
Chronic neutrophilic leukemia Microchapters |
Differentiating Chronic neutrophilic leukemia from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Chronic neutrophilic leukemia causes On the Web |
American Roentgen Ray Society Images of Chronic neutrophilic leukemia causes |
Directions to Hospitals Treating Chronic neutrophilic leukemia |
Risk calculators and risk factors for Chronic neutrophilic leukemia causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3] Associate Editor(s)-in-Chief: Homa Najafi, M.D.[4]
Overview
The etiology of Chronic neutrophilic leukemia (CNL) is unknown. An association between CNL and multiple myeloma has been suggested.
Etiology
The etiology of CNL is currently unknown. An association between CNL and multiple myeloma has been suggested based on the observation of myeloma in 20% of CNL cases.[1] However, a clonal genetic abnormality has not been detected in these myeloma-associated cases of CNL, raising the possibility that the neutrophilia is a reaction due to the neoplastic myeloma cells. The postulated cell of origin is a limited-potential, marrow-derived stem cell.[2]
References
- ↑ [1] Standen GR, Steers FJ, Jones L. "Clonality of chronic neutrophilic leukemia associated with myeloma: analysis using the X-linked probe M27 beta." J Clin Pathol. 1993 Apr;46(4):297-8. PMID: 8098719
- ↑ [2] Yanagisawa K, Ohminami H, Sato M, Takada K, Hasegawa H, Yasukawa M, Fujita S. "Neoplastic involvement of granulocytic lineage, not granulocytic-monocytic, monocytic, or erythrocytic lineage, in a patient with chronic neutrophilic leukemia." Am J Hematol. 1998 Mar;57(3):221-4. PMID: 9495373