Chronic myelogenous leukemia epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]

Overview

The incidence of Chronic Myeloid Leukemia (CML) was estimated to be 1–2 cases per 100,000 individuals worldwide. The peak age for the disease is 50 to 55. incidence in CML increases by age, at least up to 75–80 years. In children, CML is a very rare disease with an incidence of 0.6–1.2 million children/year. CML is more common in males than in females with male-to-female ratio varying between 1.2 and 1.7 in different studies. The gender difference in incidence is less prominent in younger age groups. myelogenous leukemia accounts for 15% of adult leukemias. although some series report a median age of up to 67 years.

PMID:24729196 /PMID:20221270/ PMID:25814090 /PMID:10428738

The peak age for the disease is 50 to 55.PMID:20221270The incidence in CML increases by age, at least up to 75–80 years. In children, CML is a very rare disease with an incidence of 0.6–1.2 million children/year [26].CML is more common in males than in females with male-to-female ratio varying between 1.2 and 1.7 in different studies [8, 20, 27]. The gender difference in incidence is less prominent in younger age groups.PMID:25814090Chronic myelogenous leukemia accounts for 15% of adult leukemias, has an incidence of 1 to 2 cases per 100000 population, and has a male-to-female ratio of 1.3 to 1. Incidence increases with age. The median age at presentation is 45 to 55 years, although some series report a median age of up to 67 years.PMID:10428738

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References

  1. 1.0 1.1 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.


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