Chondrosarcoma epidemiology and demographics: Difference between revisions

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{{Chondrosarcoma}}
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==Overview==
==Overview==
Chondrosarcoma is the second most common [[malignant]] primary [[tumor]] of [[bone]]. It is most frequently diagnosed in patients in their 4th and 5th decades of life. Men are slightly more affected by chondrosarcoma than women. There is no racial predilection to chondrosarcoma.
==Epidemiology and Demographics==
==Epidemiology and Demographics==
Chondrosarcomas are malignant cartilaginous tumors that account for 20-27% of all primary malignant bone tumors. Chondrosarcoma is the second most common malignant primary tumor of bone.  
===Incidence===
*Chondrosarcoma is the second most common primary [[bone]] [[sarcoma]].<ref>{{cite book | last = Peabody | first = Terrance | title = Orthopaedic oncology : primary and metastatic tumors of the skeletal system | publisher = Springer | location = Cham | year = 2014 | isbn = 9783319073224 }}</ref>
*The incidence of chondrosarcoam is approximately 1 per 100,000 individuals worldwide.<ref name="pmid30559960">{{cite journal| author=Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ| title=Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment. | journal=Clin Sarcoma Res | year= 2018 | volume= 8 | issue=  | pages= 23 | pmid=30559960 | doi=10.1186/s13569-018-0110-1 | pmc=6293503 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30559960  }} </ref>
 
===Age===
===Age===
*Chondrosarcoma is most frequently diagnosed in patients in their 4th and 5th decades of life with an average age at diagnosis of 51.
*Chondrosarcoma is most frequently diagnosed in patients in their 4th and 5th decades of life.<ref name="pmid11845358">{{cite journal| author=Unni KK| title=Cartilaginous lesions of bone. | journal=J Orthop Sci | year= 2001 | volume= 6 | issue= 5 | pages= 457-72 | pmid=11845358 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11845358  }} </ref>
*The average age at presentation is 51 years.
 
===Race===
*There is no racial predilection to chondrosarcoma.<ref name="pmid30559960">{{cite journal| author=Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ| title=Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment. | journal=Clin Sarcoma Res | year= 2018 | volume= 8 | issue=  | pages= 23 | pmid=30559960 | doi=10.1186/s13569-018-0110-1 | pmc=6293503 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30559960  }} </ref>
 
===Gender===
===Gender===
*Men are slightly more affected with chondrosarcoma than women.
*Chondrosarcoma affects men and women almost equally with slight male predominance.<ref name="pmid12180616">{{cite journal| author=Weber KL, Raymond AK| title=Low-grade/dedifferentiated/high-grade chondrosarcoma: a case of histological and biological progression. | journal=Iowa Orthop J | year= 2002 | volume= 22 | issue=  | pages= 75-80 | pmid=12180616 | doi= | pmc=1888368 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12180616  }} </ref>
*Exception to this is the clear cell sub-type which has significant male preponderance.
*The male to female ratio is almost 1:1 except for clear cell chondrosarcoma it is 2.4:1.


==References==
==References==
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Latest revision as of 14:47, 25 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Overview

Chondrosarcoma is the second most common malignant primary tumor of bone. It is most frequently diagnosed in patients in their 4th and 5th decades of life. Men are slightly more affected by chondrosarcoma than women. There is no racial predilection to chondrosarcoma.

Epidemiology and Demographics

Incidence

  • Chondrosarcoma is the second most common primary bone sarcoma.[1]
  • The incidence of chondrosarcoam is approximately 1 per 100,000 individuals worldwide.[2]

Age

  • Chondrosarcoma is most frequently diagnosed in patients in their 4th and 5th decades of life.[3]
  • The average age at presentation is 51 years.

Race

  • There is no racial predilection to chondrosarcoma.[2]

Gender

  • Chondrosarcoma affects men and women almost equally with slight male predominance.[4]
  • Exception to this is the clear cell sub-type which has significant male preponderance.
  • The male to female ratio is almost 1:1 except for clear cell chondrosarcoma it is 2.4:1.

References

  1. Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. 2.0 2.1 Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). "Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment". Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.
  3. Unni KK (2001). "Cartilaginous lesions of bone". J Orthop Sci. 6 (5): 457–72. PMID 11845358.
  4. Weber KL, Raymond AK (2002). "Low-grade/dedifferentiated/high-grade chondrosarcoma: a case of histological and biological progression". Iowa Orthop J. 22: 75–80. PMC 1888368. PMID 12180616.

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