Cholangiocarcinoma epidemiology and demographics: Difference between revisions

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{{Cholangiocarcinoma}}


{{CMG}}; {{AE}} {{F.K}} {{PSK}}  
{{CMG}}; {{AE}}{{F.K}} [mailto:fkahe@bidmc.harvard.edu], {{PSK}}  
==Overview==
==Overview==
The [[incidence]] of cholangiocarcinoma is approximately 1-2 per 100,000 individuals in the United States. The [[prevalence]] of cholangiocarcinoma is approximately 0.01% to 0.46% per 100,000 individuals. Patients of all age groups may develop cholangiocarcinoma. Cholangiocarcinoma is more common in males than in females.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
===Incidence===
*In 1973-2012, the incidence of cholangiocarcinoma was estimated to be 0.44 to 1.18 cases per 100,000 individuals worldwide.
*The [[incidence]] of cholangiocarcinoma is approximately 1-2 per 100,000 individuals in the United States.
*The highest annual incidences of cholangiocarcinoma is 5.5 cases per 100,000 people in Japan, and 7.3 cases per 100,000 people in Israel.<ref name="pmid18773060">{{cite journal |vauthors=Khan SA, Toledano MB, Taylor-Robinson SD |title=Epidemiology, risk factors, and pathogenesis of cholangiocarcinoma |journal=HPB (Oxford) |volume=10 |issue=2 |pages=77–82 |year=2008 |pmid=18773060 |pmc=2504381 |doi=10.1080/13651820801992641 |url=}}</ref>


===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*The [[prevalence]] of cholangiocarcinoma is approximately 0.01% to 0.46% per 100,000 individuals.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*The [[prevalence]] of cholangiocarcinoma in patients with [[primary sclerosing cholangitis]] may be as high as 30%, based on [[autopsy]] studies.<ref name="pmid18773060">{{cite journal |vauthors=Khan SA, Toledano MB, Taylor-Robinson SD |title=Epidemiology, risk factors, and pathogenesis of cholangiocarcinoma |journal=HPB (Oxford) |volume=10 |issue=2 |pages=77–82 |year=2008 |pmid=18773060 |pmc=2504381 |doi=10.1080/13651820801992641 |url=}}</ref><ref name="pmid25966423">{{cite journal |vauthors=Bergquist A, von Seth E |title=Epidemiology of cholangiocarcinoma |journal=Best Pract Res Clin Gastroenterol |volume=29 |issue=2 |pages=221–32 |year=2015 |pmid=25966423 |doi=10.1016/j.bpg.2015.02.003 |url=}}</ref>
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.


===Case-fatality rate/Mortality rate===
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
*The mortality rate for [[intrahepatic cholangiocarcinoma]] among men increased from 0.17 to 0.78 per 100,000 in period of 1975-1979 to 1993-1997.<ref name="pmid17457168">{{cite journal |vauthors=DeOliveira ML, Cunningham SC, Cameron JL, Kamangar F, Winter JM, Lillemoe KD, Choti MA, Yeo CJ, Schulick RD |title=Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution |journal=Ann. Surg. |volume=245 |issue=5 |pages=755–62 |year=2007 |pmid=17457168 |pmc=1877058 |doi=10.1097/01.sla.0000251366.62632.d3 |url=}}</ref>
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].
*The mortality rate for [[intrahepatic cholangiocarcinoma]] among women, increased from 0.12 to 0.57 per 100,000 in period of 1975-1979 to 1993-1997.


===Age===
===Age===
*Patients of all age groups may develop [disease name].
*Patients of all age groups may develop cholangiocarcinoma.
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*The median age at the time of cholangiocarcinoma diagnosis is 70-80 years, except in patients with [[bile duct]] cystic disorders.<ref name="Macias2014">{{cite journal|last1=Macias|first1=Rocio I. R.|title=Cholangiocarcinoma: Biology, Clinical Management, and Pharmacological Perspectives|journal=ISRN Hepatology|volume=2014|year=2014|pages=1–13|issn=2314-4041|doi=10.1155/2014/828074}}</ref>
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.  
*[[Bile duct]] cystic disorders usually develop cholangiocarcinoma much earlier, between 30 and 40 years.
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].


===Race===
===Race===
*There is no racial predilection to [disease name].
*Cholangiocarcinoma usually affects individuals of the American Indian, Alaska Natives and Asian and Pacific Islanders race.<ref name="pmid17032404">{{cite journal |vauthors=McLean L, Patel T |title=Racial and ethnic variations in the epidemiology of intrahepatic cholangiocarcinoma in the United States |journal=Liver Int. |volume=26 |issue=9 |pages=1047–53 |year=2006 |pmid=17032404 |doi=10.1111/j.1478-3231.2006.01350.x |url=}}</ref>
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
 
===Gender===
===Gender===
*[Disease name] affects men and women equally.
*Cholangiocarcinoma is more common in males than in females.<ref name="radio">Cholangiocarcinoma. Radiopaedia. http://radiopaedia.org/articles/cholangiocarcinoma</ref>
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
 
===Region===
===Region===
*The majority of [disease name] cases are reported in [geographical region].
*The majority of cholangiocarcinoma cases are reported in North America, Asia, and Australia.<ref name="pmid17032404">{{cite journal |vauthors=McLean L, Patel T |title=Racial and ethnic variations in the epidemiology of intrahepatic cholangiocarcinoma in the United States |journal=Liver Int. |volume=26 |issue=9 |pages=1047–53 |year=2006 |pmid=17032404 |doi=10.1111/j.1478-3231.2006.01350.x |url=}}</ref>
 
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
 
===Developed Countries===
 
===Developing Countries===


==References==
==References==

Latest revision as of 15:17, 12 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2] [3], Suveenkrishna Pothuru, M.B,B.S. [4]

Overview

The incidence of cholangiocarcinoma is approximately 1-2 per 100,000 individuals in the United States. The prevalence of cholangiocarcinoma is approximately 0.01% to 0.46% per 100,000 individuals. Patients of all age groups may develop cholangiocarcinoma. Cholangiocarcinoma is more common in males than in females.

Epidemiology and Demographics

Incidence

  • The incidence of cholangiocarcinoma is approximately 1-2 per 100,000 individuals in the United States.
  • The highest annual incidences of cholangiocarcinoma is 5.5 cases per 100,000 people in Japan, and 7.3 cases per 100,000 people in Israel.[1]

Prevalence

Case-fatality rate/Mortality rate

Age

  • Patients of all age groups may develop cholangiocarcinoma.
  • The median age at the time of cholangiocarcinoma diagnosis is 70-80 years, except in patients with bile duct cystic disorders.[4]
  • Bile duct cystic disorders usually develop cholangiocarcinoma much earlier, between 30 and 40 years.

Race

  • Cholangiocarcinoma usually affects individuals of the American Indian, Alaska Natives and Asian and Pacific Islanders race.[5]

Gender

  • Cholangiocarcinoma is more common in males than in females.[6]

Region

  • The majority of cholangiocarcinoma cases are reported in North America, Asia, and Australia.[5]

References

  1. ↑ 1.0 1.1 Khan SA, Toledano MB, Taylor-Robinson SD (2008). "Epidemiology, risk factors, and pathogenesis of cholangiocarcinoma". HPB (Oxford). 10 (2): 77–82. doi:10.1080/13651820801992641. PMC 2504381. PMID 18773060.
  2. ↑ Bergquist A, von Seth E (2015). "Epidemiology of cholangiocarcinoma". Best Pract Res Clin Gastroenterol. 29 (2): 221–32. doi:10.1016/j.bpg.2015.02.003. PMID 25966423.
  3. ↑ DeOliveira ML, Cunningham SC, Cameron JL, Kamangar F, Winter JM, Lillemoe KD, Choti MA, Yeo CJ, Schulick RD (2007). "Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution". Ann. Surg. 245 (5): 755–62. doi:10.1097/01.sla.0000251366.62632.d3. PMC 1877058. PMID 17457168.
  4. ↑ Macias, Rocio I. R. (2014). "Cholangiocarcinoma: Biology, Clinical Management, and Pharmacological Perspectives". ISRN Hepatology. 2014: 1–13. doi:10.1155/2014/828074. ISSN 2314-4041.
  5. ↑ 5.0 5.1 McLean L, Patel T (2006). "Racial and ethnic variations in the epidemiology of intrahepatic cholangiocarcinoma in the United States". Liver Int. 26 (9): 1047–53. doi:10.1111/j.1478-3231.2006.01350.x. PMID 17032404.
  6. ↑ Cholangiocarcinoma. Radiopaedia. http://radiopaedia.org/articles/cholangiocarcinoma

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