Chickenpox medical therapy: Difference between revisions

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====Anti-viral Therapy====
====Anti-viral Therapy====
* Anti-viral therapy for chickenpox is beneficial if given within the first 24hrs of the appearance of the rash.<ref name="urlA Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJM199111283252203#t=article |title=A Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM |format= |work= |accessdate=}}</ref><ref name="pmid1323943">{{cite journal |vauthors=Wallace MR, Bowler WA, Murray NB, Brodine SK, Oldfield EC |title=Treatment of adult varicella with oral acyclovir. A randomized, placebo-controlled trial |journal=Ann. Intern. Med. |volume=117 |issue=5 |pages=358–63 |year=1992 |pmid=1323943 |doi= |url=}}</ref><ref name="pmid26379165">{{cite journal |vauthors=Kechagia IA, Kalantzi L, Dokoumetzidis A |title=Extrapolation of Valacyclovir Posology to Children Based on Pharmacokinetic Modeling |journal=Pediatr. Infect. Dis. J. |volume=34 |issue=12 |pages=1342–8 |year=2015 |pmid=26379165 |doi=10.1097/INF.0000000000000910 |url=}}</ref>
* Anti-viral therapy with acyclovir and valcyclovir is beneficial if given within the first 24hrs of the appearance of the rash.<ref name="urlA Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJM199111283252203#t=article |title=A Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM |format= |work= |accessdate=}}</ref><ref name="pmid1323943">{{cite journal |vauthors=Wallace MR, Bowler WA, Murray NB, Brodine SK, Oldfield EC |title=Treatment of adult varicella with oral acyclovir. A randomized, placebo-controlled trial |journal=Ann. Intern. Med. |volume=117 |issue=5 |pages=358–63 |year=1992 |pmid=1323943 |doi= |url=}}</ref><ref name="pmid26379165">{{cite journal |vauthors=Kechagia IA, Kalantzi L, Dokoumetzidis A |title=Extrapolation of Valacyclovir Posology to Children Based on Pharmacokinetic Modeling |journal=Pediatr. Infect. Dis. J. |volume=34 |issue=12 |pages=1342–8 |year=2015 |pmid=26379165 |doi=10.1097/INF.0000000000000910 |url=}}</ref>


=====Medications to avoid=====
=====Medications to avoid=====

Revision as of 00:37, 30 June 2017


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Chickenpox Microchapters

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Overview

There is no definitive treatment for chicken pox, supportive treatment to minimize discomfort and pruritus.

Medical Therapy

Symptomatic treatment

  • Mild sodium bicarbonate baths, antihistamine medication to help ease itching
  • Acetaminophen to reduce fever.
  • Ibuprofen
  • ASPIRIN MUST NOT BE GIVEN to children with chickenpox to avoid potentially fatal Reye's Syndrome. [1][2]
  • Topical application of calamine lotion [3] Calamine lotion is no longer recommended due to its excessive drying nature.
  • Maintaining adequate hydration
  • Intravenous Immunoglobulin therapy is also considered in pregnant women, immunocompromised patients and newborns who are not vaccinated.

Anti-viral Therapy

  • Anti-viral therapy with acyclovir and valcyclovir is beneficial if given within the first 24hrs of the appearance of the rash.[4][5][6]
Medications to avoid

References

  1. US Centers for Disease Control and Prevention. "Varicella Treatment Questions & Answers". CDC Guidelines. CDC. Retrieved 2007-8-23. Check date values in: |accessdate= (help)
  2. Somekh E, Dalal I, Shohat T, Ginsberg GM, Romano O (2002). "The burden of uncomplicated cases of chickenpox in Israel". J. Infect. 45 (1): 54–7. PMID 12217733.
  3. Tebruegge M, Kuruvilla M, Margarson I (2006). "Does the use of calamine or antihistamine provide symptomatic relief from pruritus in children with varicella zoster infection?". Arch. Dis. Child. 91 (12): 1035–6. doi:10.1136/adc.2006.105114. PMID 17119083. Text "format-Abstract" ignored (help)
  4. "A Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM".
  5. Wallace MR, Bowler WA, Murray NB, Brodine SK, Oldfield EC (1992). "Treatment of adult varicella with oral acyclovir. A randomized, placebo-controlled trial". Ann. Intern. Med. 117 (5): 358–63. PMID 1323943.
  6. Kechagia IA, Kalantzi L, Dokoumetzidis A (2015). "Extrapolation of Valacyclovir Posology to Children Based on Pharmacokinetic Modeling". Pediatr. Infect. Dis. J. 34 (12): 1342–8. doi:10.1097/INF.0000000000000910. PMID 26379165.


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