Carcinoma of the penis classification
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Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Swathi Venkatesan, M.B.B.S.[2]
Overview
Carcinoma of the penis may be classified according to cell types into several subtypes: squamous cell carcinoma, adenocarcinoma, melanoma, basal cell carcinoma, lymphoma, and sarcoma.
Classification
Most common malignant penile tumours
- The most common type of penile cancer is squamous cell carcinoma (SCC).
- There are several subtypes of SCC:
- Warty carcinoma (verruciform) and verrucous carcinoma
- Looks like a genital wart and may have a cauliflower-like appearance
- Usually slow growing, but they gradually enlarge and can spread deeply into surrounding tissue
- Rarely spread to lymph nodes or other parts of the body
- Often associated with human papillomavirus (HPV) infection
- Basaloid carcinoma
- Uncommon type of squamous cell penile cancer
- Fast growing
- Sarcomatoid carcinoma
- Fast growing
Rare malignant penile tumours
- There are several rare types of penile cancer:
Adenocarcinoma"Penile Cancer: Introduction | Cancer.Net".
- Develops from sweat glands (glandular cells) in the skin of the penis
- Occurs much less often than SCC
- Also called Paget's disease of the penis
Melanoma
- Develops from skin cells called melanocytes
- Usually develops on sun-exposed areas of skin, but sometimes develops on the penis
Basal cell carcinoma
- A type of non-melanoma skin cancer
- Slow growing and rarely spreads to other areas of the body
Lymphoma
- A type of cancer that starts in immune cells of the lymphatic system
Sarcoma
- A type of cancer that starts in connective tissues (tissue that surrounds and supports various organs in the body)
- Starts in the connective and supporting tissues of the body
- Tends to be fast growing
- May include AIDS-related Kaposi sarcoma (KS)
References
- ↑ Malignant tumours of the penis. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/penile/penile-cancer/malignant-tumours/?region=ab
- ↑ Cubilla AL, Velazquez EF, Amin MB, Epstein J, Berney DM, Corbishley CM; et al. (2018). "The World Health Organisation 2016 classification of penile carcinomas: a review and update from the International Society of Urological Pathology expert-driven recommendations". Histopathology. 72 (6): 893–904. doi:10.1111/his.13429. PMID 29105175.