CDKL2: Difference between revisions
Jump to navigation
Jump to search
m (Bot: HTTP→HTTPS) |
(→top: Adding wikilinks; removed {{Underlinked|date=May 2016}} tag) |
||
| Line 1: | Line 1: | ||
{{Infobox_gene}} | {{Infobox_gene}} | ||
'''Cyclin-dependent kinase-like 2''' is an [[enzyme]] that in humans is encoded by the ''CDKL2'' [[gene]].<ref name="pmid9000130">{{cite journal | vauthors = Taglienti CA, Wysk M, Davis RJ | title = Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE | journal = Oncogene | volume = 13 | issue = 12 | pages = 2563–74 |date=Feb 1997 | pmid = 9000130 | pmc = | doi = }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8999| accessdate = }}</ref> | '''Cyclin-dependent kinase-like 2''' is an [[enzyme]] that in humans is encoded by the ''CDKL2'' [[gene]].<ref name="pmid9000130">{{cite journal | vauthors = Taglienti CA, Wysk M, Davis RJ | title = Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE | journal = Oncogene | volume = 13 | issue = 12 | pages = 2563–74 |date=Feb 1997 | pmid = 9000130 | pmc = | doi = }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8999| accessdate = }}</ref> | ||
| Line 6: | Line 5: | ||
{{PBB_Summary | {{PBB_Summary | ||
| section_title = | | section_title = | ||
| summary_text = This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.<ref name="entrez"/> | | summary_text = This [[gene product]] is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the [[cytoplasm]], with lower levels in the [[cell nucleus|nucleus]].<ref name="entrez"/> | ||
}} | }} | ||
Revision as of 00:08, 15 May 2018
| VALUE_ERROR (nil) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Aliases | |||||||
| External IDs | GeneCards: [1] | ||||||
| Orthologs | |||||||
| Species | Human | Mouse | |||||
| Entrez |
|
| |||||
| Ensembl |
|
| |||||
| UniProt |
|
| |||||
| RefSeq (mRNA) |
|
| |||||
| RefSeq (protein) |
|
| |||||
| Location (UCSC) | n/a | n/a | |||||
| PubMed search | n/a | n/a | |||||
| Wikidata | |||||||
| |||||||
Cyclin-dependent kinase-like 2 is an enzyme that in humans is encoded by the CDKL2 gene.[1][2]
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.[2]
References
External links
- Human CDKL2 genome location and CDKL2 gene details page in the UCSC Genome Browser.
Further reading
- Marracci GH, Marquardt WE, Strehlow A, et al. (2006). "Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck)". Biochem. Biophys. Res. Commun. 344 (3): 963–971. doi:10.1016/j.bbrc.2006.03.172. PMID 16631599.
- Sarkar SN, Peters KL, Elco CP, et al. (2004). "Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling". Nat. Struct. Mol. Biol. 11 (11): 1060–1067. doi:10.1038/nsmb847. PMID 15502848.
- Tao J, Van Esch H, Hagedorn-Greiwe M, et al. (2005). "Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5/STK9) gene are associated with severe neurodevelopmental retardation". Am. J. Hum. Genet. 75 (6): 1149–1154. doi:10.1086/426460. PMC 1182152. PMID 15499549.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
- Marcilla A, Rivero-Lezcano OM, Agarwal A, Robbins KC (1995). "Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors". J. Biol. Chem. 270 (16): 9115–9120. doi:10.1074/jbc.270.16.9115. PMID 7721825.
 | This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it. |