Brain abscess natural history, complications and prognosis: Difference between revisions
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Brain abscesses can result from a decline in consciousness. This can be catalyzed by [[seizures]] or [[status epilepticus]]. If there is an abscess rupture into the ventricular system, [[ventriculitis]] can ensue. Over the past 50 years, the prognosis for patients with brain abscesses has improved significantly. These advances include further knowledge of cranial imaging techniques, antimicrobial treatment regimens, and the introduction of minimally invasive neurosurgical procedures. <ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> | Brain abscesses can result from a decline in consciousness. This can be catalyzed by [[seizures]] or [[status epilepticus]]. If there is an abscess rupture into the ventricular system, [[ventriculitis]] can ensue. Over the past 50 years, the prognosis for patients with brain abscesses has improved significantly. These advances include further knowledge of cranial imaging techniques, antimicrobial treatment regimens, and the introduction of minimally invasive neurosurgical procedures. <ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> | ||
==Natural History== | |||
While the mortality rate was 40% in 1960, it has dropped down to 15% within the past decade alone. <ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> | |||
==Complications== | ==Complications== | ||
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==Prognosis== | ==Prognosis== | ||
70% of patients with brain abscesses have a good outcome, rarely with minimal neurological [[sequelae]]. <ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> | |||
==References== | ==References== | ||
Revision as of 19:07, 2 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Brain abscesses can result from a decline in consciousness. This can be catalyzed by seizures or status epilepticus. If there is an abscess rupture into the ventricular system, ventriculitis can ensue. Over the past 50 years, the prognosis for patients with brain abscesses has improved significantly. These advances include further knowledge of cranial imaging techniques, antimicrobial treatment regimens, and the introduction of minimally invasive neurosurgical procedures. [1]
Natural History
While the mortality rate was 40% in 1960, it has dropped down to 15% within the past decade alone. [1]
Complications
Common complications as a result of lack of consciousness include: [1]
- Hydrocephalus (also resulting from abscesses in the posterior fossa)
- Brain herniation
Prognosis
70% of patients with brain abscesses have a good outcome, rarely with minimal neurological sequelae. [1]
References
- ↑ 1.0 1.1 1.2 1.3 Brouwer MC, Tunkel AR, McKhann GM, van de Beek D (2014). "Brain abscess". N Engl J Med. 371 (5): 447–56. doi:10.1056/NEJMra1301635. PMID 25075836.