Bladder cancer classification: Difference between revisions
No edit summary |
|||
| Line 1: | Line 1: | ||
{{Bladder cancer}} | {{Bladder cancer}} | ||
{{SCC}} | {{SCC}} | ||
==Pathological Classification== | ==Pathological Classification== | ||
90% of bladder cancer are [[Transitional cell carcinoma]]s (TCC) that arise from the inner lining of the bladder called the[[urothelium]]. The other 10% of tumours are [[squamous cell carcinoma]], [[adenocarcinoma]], [[sarcoma]], [[small cell carcinoma]]and secondary deposits from cancers elsewhere in the body. | 90% of bladder cancer are [[Transitional cell carcinoma]]s (TCC) that arise from the inner lining of the bladder called the[[urothelium]]. The other 10% of tumours are [[squamous cell carcinoma]], [[adenocarcinoma]], [[sarcoma]], [[small cell carcinoma]]and secondary deposits from cancers elsewhere in the body. | ||
Revision as of 22:04, 19 January 2012
|
Bladder cancer Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Bladder cancer classification On the Web |
|
American Roentgen Ray Society Images of Bladder cancer classification |
|
Risk calculators and risk factors for Bladder cancer classification |
Steven C. Campbell, M.D., Ph.D.
Pathological Classification
90% of bladder cancer are Transitional cell carcinomas (TCC) that arise from the inner lining of the bladder called theurothelium. The other 10% of tumours are squamous cell carcinoma, adenocarcinoma, sarcoma, small cell carcinomaand secondary deposits from cancers elsewhere in the body.
TCCs are often multifocal, with 30-40% of patients having a more than one tumour at diagnosis. The pattern of growth of TCCs can be papillary, sessile (flat) or carcinoma-in-situ (CIS).
The 1973 WHO grading system for TCCs (papilloma, G1, G2 or G3) is most commonly used despite being superseded by the 2004 WHO[1] grading (papillary neoplasm of low malignant potential (PNLMP), low grade and high grade papillary carcinoma.
CIS invariably consists of cytologically high grade tumour cells.
Bladder TCC is staged according to the 1997 TNM system:
- Ta Non-invasive papillary tumour
- T1 Invasive but not as far as the muscular bladder layer
- T2 Invasive into the muscular layer
- T3 Invasive beyond the muscle into the fat outside the bladder
- T4 Invasive into surrounding structures like the prostate, uterus or pelvic wall
References
- ↑ Sauter G, Algaba F, Amin MB, Busch C, Cheville J, Gasser T, Grignon D, Hofstaedter F, Lopez-Beltran A, Epstein JI. Noninvasive urothelial neoplasias: WHO classification of noninvasive papillary urothelial tumors. In World Health Organization classification of tumors. Pathology and genetics of tumors of the urinary system and male genital organs. Eble JN, Epstein JI, Sesterhenn I (eds): Lyon, IARCC Press, p. 110, 2004
bs:Rak mokraćnog mjehura da:Blærecancer de:Blasenkrebs hr:Rak mokraćnog mjehura no:Urinveiskreft fi:Virtsarakon syöpä sv:Urinvägscancer