Benfluorex

Benfluorex
Clinical data
Routes of; administration	Oral
ATC code	C10AX04 (WHO) ;
Pharmacokinetic data
Excretion	Renal
Identifiers
	IUPAC name 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]; ethyl benzoate;
CAS Number	23602-78-0;
PubChem CID	2318;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C19H20F3NO2
Molar mass	351.363 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Benfluorex is an anorectic and hypolipidemic agent. Clinical studies have shown it may improve glycemic control and decrease insulin resistance in people with poorly controlled type 2 diabetes;^[1]^[2] it is marketed in France as an adjuvant antidiabetic.

Benfluorex is structurally related to fenfluramine.

References

↑ Moulin P, Andre M, Alawi H; et al. (2006). "Efficacy of benfluorex in combination with sulfonylurea in type 2 diabetic patients: an 18-week, randomized, double-blind study". Diabetes Care. 29 (3): 515–20. PMID 16505498. Free full text
↑ Roger P, Auclair J, Drain P (1999). "Addition of benfluorex to biguanide improves glycemic control in obese non-insulin-dependent diabetes: a double-blind study versus placebo". J Diabetes Complications. 13 (2): 62–7. PMID 10432168.

Template:Lipid modifying agents Template:SIB

Template:WikiDoc Sources

[1] Moulin P, Andre M, Alawi H; et al. (2006). "Efficacy of benfluorex in combination with sulfonylurea in type 2 diabetic patients: an 18-week, randomized, double-blind study". Diabetes Care. 29 (3): 515–20. PMID 16505498. Free full text

[2] Roger P, Auclair J, Drain P (1999). "Addition of benfluorex to biguanide improves glycemic control in obese non-insulin-dependent diabetes: a double-blind study versus placebo". J Diabetes Complications. 13 (2): 62–7. PMID 10432168.

[1]

[2]

Clinical data

Routes of administration	Oral
ATC code	C10AX04 (WHO)
Pharmacokinetic data
Excretion	Renal
Identifiers
IUPAC name 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino] ethyl benzoate
CAS Number	23602-78-0
PubChem CID	2318
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₉H₂₀F₃NO₂
Molar mass	351.363 g/mol

Benfluorex

Overview

References

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