Autoimmune hepatitis historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
===Discovery=== | ===Discovery=== | ||
*Autoimmune hepatitis was the first to describe early in the 1950s, under the name lupoid hepatitis, which mainly affects young women.<ref name="pmid13386250">{{cite journal |vauthors=COWLING DC, MACKAY IR, TAFT LI |title=Lupoid hepatitis |journal=Lancet |volume=271 |issue=6957 |pages=1323–6 |year=1956 |pmid=13386250 |doi= |url=}}</ref> | *[[Autoimmune hepatitis]] was the first to describe early in the 1950s, under the name [[lupoid hepatitis]], which mainly affects young women.<ref name="pmid13386250">{{cite journal |vauthors=COWLING DC, MACKAY IR, TAFT LI |title=Lupoid hepatitis |journal=Lancet |volume=271 |issue=6957 |pages=1323–6 |year=1956 |pmid=13386250 |doi= |url=}}</ref> | ||
*In 1950, Waldenstrom described a form of chronic hepatitis in young women.<ref name="pmid13150939">{{cite journal |vauthors=WALDENSTROM J |title=[Liver, blood proteins and nutritive protein] |language=Undetermined |journal=Dtsch Z Verdau Stoffwechselkr |volume=9 |issue= |pages=113–9 |year=1953 |pmid=13150939 |doi= |url=}}</ref> | *In 1950, Waldenstrom described a form of [[chronic hepatitis]] in young [[women]].<ref name="pmid13150939">{{cite journal |vauthors=WALDENSTROM J |title=[Liver, blood proteins and nutritive protein] |language=Undetermined |journal=Dtsch Z Verdau Stoffwechselkr |volume=9 |issue= |pages=113–9 |year=1953 |pmid=13150939 |doi= |url=}}</ref> | ||
*In 1950, Kunkel, and in 1956, Bearn, described features of the disease, including hepatosplenomegaly, jaundice, acne, hirsutism, cushingoid facies, pigmented abdominal striae, obesity, arthritis, and amenorrhea. | *In 1950, Kunkel, and in 1956, Bearn, described features of the disease, including [[hepatosplenomegaly]], [[jaundice]], [[acne]], [[hirsutism]], [[Cushingoid appearance|cushingoid]] facies, pigmented [[abdominal]] [[striae]], [[obesity]], [[arthritis]], and [[amenorrhea]]. | ||
*In 1992, an international panel described the diagnostic criteria for Autoimmune hepatitis. | *In 1992, an international panel described the diagnostic criteria for Autoimmune hepatitis. | ||
*The term Autoimmune hepatitis was used to replace terms such as Autoimmune liver disease and Autoimmune chronic active hepatitis by an international panel. | *The term Autoimmune hepatitis was used to replace terms such as Autoimmune liver disease and Autoimmune chronic active hepatitis by an international panel. |
Revision as of 17:15, 27 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: :Manpreet Kaur, MD [2]
Overview
Historical Perspective
Discovery
- Autoimmune hepatitis was the first to describe early in the 1950s, under the name lupoid hepatitis, which mainly affects young women.[1]
- In 1950, Waldenstrom described a form of chronic hepatitis in young women.[2]
- In 1950, Kunkel, and in 1956, Bearn, described features of the disease, including hepatosplenomegaly, jaundice, acne, hirsutism, cushingoid facies, pigmented abdominal striae, obesity, arthritis, and amenorrhea.
- In 1992, an international panel described the diagnostic criteria for Autoimmune hepatitis.
- The term Autoimmune hepatitis was used to replace terms such as Autoimmune liver disease and Autoimmune chronic active hepatitis by an international panel.
- C4 gene mutations were first implicated in the pathogenesis of Autoimmune hepatitis.[3]
Landmark Events in the Development of Treatment Strategies
- In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
References
- ↑ COWLING DC, MACKAY IR, TAFT LI (1956). "Lupoid hepatitis". Lancet. 271 (6957): 1323–6. PMID 13386250.
- ↑ WALDENSTROM J (1953). "[Liver, blood proteins and nutritive protein]". Dtsch Z Verdau Stoffwechselkr (in Undetermined). 9: 113–9. PMID 13150939.
- ↑ Scully LJ, Toze C, Sengar DP, Goldstein R (1993). "Early-onset autoimmune hepatitis is associated with a C4A gene deletion". Gastroenterology. 104 (5): 1478–84. PMID 8482459.