Asperger syndrome differential diagnosis: Difference between revisions

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== Overview ==
== Overview ==
There are several differential diagnosis to consider in the diagnosis of Asperger Syndrome (AS) including attention deficit–hyperactivity disorder (ADHD), obsessive compulsive disorder (OCD), schizophrenia, schizoid personality disorder, schizotypal personality disorder and mood disorders.<ref name="pmid24290364" /><ref name="FitzgeraldCorvin2018" />
There are several differential diagnosis to consider in the diagnosis of Asperger Syndrome (AS) including attention deficit–hyperactivity disorder (ADHD), obsessive compulsive disorder (OCD), schizophrenia, schizoid personality disorder, schizotypal personality disorder and mood disorders.<ref name="pmid24290364">{{cite journal| author=Lehnhardt FG, Gawronski A, Pfeiffer K, Kockler H, Schilbach L, Vogeley K| title=The investigation and differential diagnosis of Asperger syndrome in adults. | journal=Dtsch Arztebl Int | year= 2013 | volume= 110 | issue= 45 | pages= 755-63 | pmid=24290364 | doi=10.3238/arztebl.2013.0755 | pmc=3849991 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24290364  }} </ref><ref name="FitzgeraldCorvin2018">{{cite journal|last1=Fitzgerald|first1=Michael|last2=Corvin|first2=Aiden|title=Diagnosis and differential diagnosis of Asperger syndrome|journal=Advances in Psychiatric Treatment|volume=7|issue=4|year=2018|pages=310–318|issn=1355-5146|doi=10.1192/apt.7.4.310}}</ref>


==Differential Diagnosis of Asperger Syndrome==
==Differential Diagnosis of Asperger Syndrome==


* Conditions that must be considered in a [[differential diagnosis]] include:
* Conditions that must be considered in a [[differential diagnosis]] include:<ref name="pmid24290364" /><ref name="FitzgeraldCorvin2018" />
**[[Autism|Autism spectrum disorder (ASD)]]<ref name="FitzgeraldCorvin2018">{{cite journal|last1=Fitzgerald|first1=Michael|last2=Corvin|first2=Aiden|title=Diagnosis and differential diagnosis of Asperger syndrome|journal=Advances in Psychiatric Treatment|volume=7|issue=4|year=2018|pages=310–318|issn=1355-5146|doi=10.1192/apt.7.4.310}}</ref><ref name="pmid24290364">{{cite journal| author=Lehnhardt FG, Gawronski A, Pfeiffer K, Kockler H, Schilbach L, Vogeley K| title=The investigation and differential diagnosis of Asperger syndrome in adults. | journal=Dtsch Arztebl Int | year= 2013 | volume= 110 | issue= 45 | pages= 755-63 | pmid=24290364 | doi=10.3238/arztebl.2013.0755 | pmc=3849991 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24290364  }} </ref>
**[[Autism|Autism spectrum disorder (ASD)]]
**[[ADHD|Attention deficit–hyperactivity disorder (ADHD)]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[ADHD|Attention deficit–hyperactivity disorder (ADHD)]]
**[[Obsessive compulsive disorder|Obsessive compulsive disorder (OCD)]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Obsessive compulsive disorder|Obsessive compulsive disorder (OCD)]]
**[[Schizophrenia]]<ref name="FitzgeraldCorvin2018" />
**[[Schizophrenia]]
**Schizophrenia simplex<ref name="pmid24290364" />
**Schizophrenia simplex
**Residual schizophrenia<ref name="pmid24290364" />
**Residual schizophrenia
**[[Schizoid personality disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Schizoid personality disorder]]
**[[Schizotypal personality disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Schizotypal personality disorder]]
**[[Semantic pragmatic disorder]]<ref name="FitzgeraldCorvin2018" />
**[[Semantic pragmatic disorder]]
**[[Nonverbal learning disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Nonverbal learning disorder]]
**Mood disorders (depression and anxiety)<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**Mood disorders (depression and anxiety)
**[[Stereotypic movement disorder]]<ref name="FitzgeraldCorvin2018" />
**[[Stereotypic movement disorder]]
**[[Alexithymia]]<ref name="pmid24290364" />
**[[Alexithymia]]
**[[Avoidant personality disorder]]<ref name="pmid24290364" />
**[[Avoidant personality disorder]]
**[[Antisocial personality disorder]]<ref name="pmid24290364" />
**[[Antisocial personality disorder]]
**[[Borderline personality disorder]]<ref name="pmid24290364" />
**[[Borderline personality disorder]]
**[[Narcissistic personality disorder]]<ref name="pmid24290364" />
**[[Narcissistic personality disorder]]
**[[Nonverbal learning disorder]]<ref name="pmid24290364" />
**[[Nonverbal learning disorder]]
**[[Post traumatic stress disorder|Post traumatic stress disorder (PTSD)]]<ref name="pmid24290364" />
**[[Post traumatic stress disorder|Post traumatic stress disorder (PTSD)]]
**[[Social phobia]]<ref name="pmid24290364" />
**[[Social phobia]]
**Compulsive (anankastic) personality disorder<ref name="pmid24290364" />
**Compulsive (anankastic) personality disorder


* The following table shows the overlap of some differential diagnoses of AS that have abnormal social interaction:<ref name="pmid24290364" />
* The following table shows the overlap of some differential diagnoses of AS that have abnormal social interaction:<ref name="pmid24290364" />

Revision as of 15:34, 16 July 2020


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]

Overview

There are several differential diagnosis to consider in the diagnosis of Asperger Syndrome (AS) including attention deficit–hyperactivity disorder (ADHD), obsessive compulsive disorder (OCD), schizophrenia, schizoid personality disorder, schizotypal personality disorder and mood disorders.[1][2]

Differential Diagnosis of Asperger Syndrome

  • The following table shows the overlap of some differential diagnoses of AS that have abnormal social interaction:[1]
Some Differential Diagnosis of Asperger Syndrome

(Modified Table from The Investigation and Differential Diagnosis of Asperger Syndrome in Adults)[1]

Asperger Syndrome Schizoid Personality Disorder Schizotypal Personality Disorder Avoidant Personality Disorder Social Phobia Obsessive Personality Disorder Obsessive-compulsive disorder (OCD) Attention deficit–hyperactivity disorder (ADHD)
Abnormal social interaction + + + + + + + +
Abnormal verbal communication + + + - - - - -
Abnormal facial expression/gestures/prosody + + + + +/-  - - +/- 
Abnormal eye contact + + +/-  + +/-  - - +/- 
Abnormal theory of mind + +/-  +/-  +/-  +/-  +/-  - +/- 
Abnormal empathy + +/-  +/-  - - +/-  - +/- 
Abnormal interests/rituals/compulsions + +/-  +/-  - - + + -
Abnormal attention +/-  - - - - - - +
Abnormal psychomotor function + - +/-  - - - - +/- 
Abnormal self-injurious behavior +/- +/-  +/-  - - - - +/- 
Abnormal psychotic manifestations +/- - +/-  - - - - -
Abnormal social interaction in childhood + +/-  +/-  +/-  - - - +
Abnormal biographical stress factors - + +/-  + +/-  + +/-  +/- 

References

  1. 1.0 1.1 1.2 1.3 Lehnhardt FG, Gawronski A, Pfeiffer K, Kockler H, Schilbach L, Vogeley K (2013). "The investigation and differential diagnosis of Asperger syndrome in adults". Dtsch Arztebl Int. 110 (45): 755–63. doi:10.3238/arztebl.2013.0755. PMC 3849991. PMID 24290364.
  2. 2.0 2.1 Fitzgerald, Michael; Corvin, Aiden (2018). "Diagnosis and differential diagnosis of Asperger syndrome". Advances in Psychiatric Treatment. 7 (4): 310–318. doi:10.1192/apt.7.4.310. ISSN 1355-5146.


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