Asperger syndrome differential diagnosis: Difference between revisions

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==Differential Diagnosis of Asperger Syndrome==
==Differential Diagnosis of Asperger Syndrome==
Conditions that must be considered in a [[differential diagnosis]] include
*[[Autism|Autism spectrum disorder (ASD)]]<ref name="FitzgeraldCorvin2018">{{cite journal|last1=Fitzgerald|first1=Michael|last2=Corvin|first2=Aiden|title=Diagnosis and differential diagnosis of Asperger syndrome|journal=Advances in Psychiatric Treatment|volume=7|issue=4|year=2018|pages=310–318|issn=1355-5146|doi=10.1192/apt.7.4.310}}</ref><ref name="pmid24290364">{{cite journal| author=Lehnhardt FG, Gawronski A, Pfeiffer K, Kockler H, Schilbach L, Vogeley K| title=The investigation and differential diagnosis of Asperger syndrome in adults. | journal=Dtsch Arztebl Int | year= 2013 | volume= 110 | issue= 45 | pages= 755-63 | pmid=24290364 | doi=10.3238/arztebl.2013.0755 | pmc=3849991 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24290364  }} </ref>
* [[ADHD|Attention deficit–hyperactivity disorder (ADHD)]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
* [[Obsessive compulsive disorder|Obsessive compulsive disorder (OCD)]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
*[[Schizophrenia]]<ref name="FitzgeraldCorvin2018" />
*Schizophrenia simplex<ref name="pmid24290364" />
*Residual schizophrenia<ref name="pmid24290364" />
*[[Schizoid personality disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
*[[Schizotypal personality disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
*[[Semantic pragmatic disorder]]<ref name="FitzgeraldCorvin2018" />
*[[Nonverbal learning disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
*Mood disorders (depression and anxiety)<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
* [[Stereotypic movement disorder]]<ref name="FitzgeraldCorvin2018" />
*[[Alexithymia]]<ref name="pmid24290364" />
*[[Avoidant personality disorder]]<ref name="pmid24290364" />
*[[Antisocial personality disorder]]<ref name="pmid24290364" />
*[[Borderline personality disorder]]<ref name="pmid24290364" />
*[[Narcissistic personality disorder]]<ref name="pmid24290364" />
*[[Nonverbal learning disorder]]<ref name="pmid24290364" />
*[[Post traumatic stress disorder|Post traumatic stress disorder (PTSD)]]<ref name="pmid24290364" />
*[[Social phobia]]<ref name="pmid24290364" />
*Compulsive (anankastic) personality disorder


== Overview ==
* Conditions that must be considered in a [[differential diagnosis]] include
<br />
 
**[[Autism|Autism spectrum disorder (ASD)]]<ref name="FitzgeraldCorvin2018">{{cite journal|last1=Fitzgerald|first1=Michael|last2=Corvin|first2=Aiden|title=Diagnosis and differential diagnosis of Asperger syndrome|journal=Advances in Psychiatric Treatment|volume=7|issue=4|year=2018|pages=310–318|issn=1355-5146|doi=10.1192/apt.7.4.310}}</ref><ref name="pmid24290364">{{cite journal| author=Lehnhardt FG, Gawronski A, Pfeiffer K, Kockler H, Schilbach L, Vogeley K| title=The investigation and differential diagnosis of Asperger syndrome in adults. | journal=Dtsch Arztebl Int | year= 2013 | volume= 110 | issue= 45 | pages= 755-63 | pmid=24290364 | doi=10.3238/arztebl.2013.0755 | pmc=3849991 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24290364  }} </ref>
**[[ADHD|Attention deficit–hyperactivity disorder (ADHD)]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Obsessive compulsive disorder|Obsessive compulsive disorder (OCD)]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Schizophrenia]]<ref name="FitzgeraldCorvin2018" />
**Schizophrenia simplex<ref name="pmid24290364" />
**Residual schizophrenia<ref name="pmid24290364" />
**[[Schizoid personality disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Schizotypal personality disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Semantic pragmatic disorder]]<ref name="FitzgeraldCorvin2018" />
**[[Nonverbal learning disorder]]<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**Mood disorders (depression and anxiety)<ref name="FitzgeraldCorvin2018" /><ref name="pmid24290364" />
**[[Stereotypic movement disorder]]<ref name="FitzgeraldCorvin2018" />
**[[Alexithymia]]<ref name="pmid24290364" />
**[[Avoidant personality disorder]]<ref name="pmid24290364" />
**[[Antisocial personality disorder]]<ref name="pmid24290364" />
**[[Borderline personality disorder]]<ref name="pmid24290364" />
**[[Narcissistic personality disorder]]<ref name="pmid24290364" />
**[[Nonverbal learning disorder]]<ref name="pmid24290364" />
**[[Post traumatic stress disorder|Post traumatic stress disorder (PTSD)]]<ref name="pmid24290364" />
**[[Social phobia]]<ref name="pmid24290364" />
**Compulsive (anankastic) personality disorder
 
* The following table shows the phenomenological overlap of some differential diagnoses of AS that have abnormal social interaction:<ref name="pmid24290364" />
 
{| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
{| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
|+
|+
|-
|-
| colspan="5" style="background: #4479BA; text-align: center;" | {{fontcolor|#000|Some Differential Diagnosis of Asperger Syndrome
| colspan="9" style="background: #4479BA; text-align: center;" |{{fontcolor|#000|Some Differential Diagnosis of Asperger Syndrome
(Modified Table from The Investigation and Differential Diagnosis of Asperger Syndrome in Adults)<ref name="pmid24290364" /> '''}}
(Modified Table from The Investigation and Differential Diagnosis of Asperger Syndrome in Adults)<ref name="pmid24290364" /> '''}}
|-style="padding: 5px 5px; background: #4479BA;" align="center" |
|- style="padding: 5px 5px; background: #4479BA;" align="center" |
|style="padding: 5px 5px; background: #4479BA;" align="center" |
| style="padding: 5px 5px; background: #4479BA;" align="center" |
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Asperger Syndrome'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Asperger Syndrome'''
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Schizoid Personality Disorder'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Schizoid Personality Disorder'''
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Schizotypal Personality Disorder'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Schizotypal Personality Disorder'''
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Avoidant Personality Disorder'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Avoidant Personality Disorder'''
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Social Phobia'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Social Phobia'''
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Obsessive Personality Disorder'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Obsessive Personality Disorder'''
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Obsessive-compulsive disorder (OCD)'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Obsessive-compulsive disorder (OCD)'''
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Attention deficit–hyperactivity disorder (ADHD)'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Attention deficit–hyperactivity disorder (ADHD)'''
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal social interaction'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal social interaction'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal verbal communication'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal verbal communication'''
|style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal facial expression/gestures/prosody'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal facial expression/gestures/prosody'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal eye contact'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal eye contact'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal theory of mind'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal theory of mind'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal empathy'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal empathy'''
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal interests/rituals/compulsions'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal interests/rituals/compulsions'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal attention'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal attention'''
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal  psychomotor function'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal  psychomotor function'''
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal self-injurious behavior'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal self-injurious behavior'''
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/-
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- <br />
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- <br />
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal psychotic manifestations'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal psychotic manifestations'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/-
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal social interaction in childhood'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal social interaction in childhood'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| -
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
|-
|-
|style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal biographical stress factors'''
| style="padding: 5px 5px; background: #4479BA;" align="center" |'''Abnormal biographical stress factors'''
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | -
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +
| style="padding: 5px 5px; background: #DCDCDC;" align="center"|+/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
|style="padding: 5px 5px; background: #DCDCDC;" align="center"| +/- 
| style="padding: 5px 5px; background: #DCDCDC;" align="center" | +/- 
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Revision as of 11:33, 20 June 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

There are several differential diagnosis to consider in the diagnosis of Asperger Syndrome (AS).

Differential Diagnosis of Asperger Syndrome

  • The following table shows the phenomenological overlap of some differential diagnoses of AS that have abnormal social interaction:[2]
Some Differential Diagnosis of Asperger Syndrome

(Modified Table from The Investigation and Differential Diagnosis of Asperger Syndrome in Adults)[2]

Asperger Syndrome Schizoid Personality Disorder Schizotypal Personality Disorder Avoidant Personality Disorder Social Phobia Obsessive Personality Disorder Obsessive-compulsive disorder (OCD) Attention deficit–hyperactivity disorder (ADHD)
Abnormal social interaction + + + + + + + +
Abnormal verbal communication + + + - - - - -
Abnormal facial expression/gestures/prosody + + + + +/-  - - +/- 
Abnormal eye contact + + +/-  + +/-  - - +/- 
Abnormal theory of mind + +/-  +/-  +/-  +/-  +/-  - +/- 
Abnormal empathy + +/-  +/-  - - +/-  - +/- 
Abnormal interests/rituals/compulsions + +/-  +/-  - - + + -
Abnormal attention +/-  - - - - - - +
Abnormal psychomotor function + - +/-  - - - - +/- 
Abnormal self-injurious behavior +/- +/-  +/-  - - - - +/- 
Abnormal psychotic manifestations +/- - +/-  - - - - -
Abnormal social interaction in childhood + +/-  +/-  +/-  - - - +
Abnormal biographical stress factors - + +/-  + +/-  + +/-  +/- 

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Fitzgerald, Michael; Corvin, Aiden (2018). "Diagnosis and differential diagnosis of Asperger syndrome". Advances in Psychiatric Treatment. 7 (4): 310–318. doi:10.1192/apt.7.4.310. ISSN 1355-5146.
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 Lehnhardt FG, Gawronski A, Pfeiffer K, Kockler H, Schilbach L, Vogeley K (2013). "The investigation and differential diagnosis of Asperger syndrome in adults". Dtsch Arztebl Int. 110 (45): 755–63. doi:10.3238/arztebl.2013.0755. PMC 3849991. PMID 24290364.


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