Anaphylaxis epidemiology and demographics: Difference between revisions

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==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.


===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
 
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*In 2006, the lifetime [[prevalence]] of [[Anaphylaxis]] was estimated to be 0.05% to 2% in the United States. However it is believed that this is an underestimation because the [[disease]] is underdiagnosed. <ref name="pmid28800865">{{cite journal| author=LoVerde D, Iweala OI, Eginli A, Krishnaswamy G| title=Anaphylaxis. | journal=Chest | year= 2018 | volume= 153 | issue= 2 | pages= 528-543 | pmid=28800865 | doi=10.1016/j.chest.2017.07.033 | pmc=6026262 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28800865  }} </ref>
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.


===Case-fatality rate/Mortality rate===
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
 
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].
*The [[mortality rate]] of [[Anaphylaxis]] is approximately 186 to 225 deaths/year. <ref name="pmid24332862">{{cite journal| author=Ma L, Danoff TM, Borish L| title=Case fatality and population mortality associated with anaphylaxis in the United States. | journal=J Allergy Clin Immunol | year= 2014 | volume= 133 | issue= 4 | pages= 1075-83 | pmid=24332862 | doi=10.1016/j.jaci.2013.10.029 | pmc=3972293 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24332862  }} </ref>


===Age===
===Age===
*Patients of all age groups may develop [disease name].
 
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*Patients of all age groups may develop [[anaphylaxis]], however, children and adolescents account for the majority of cases.<ref name="pmid17165265">{{cite journal| author=Lieberman P, Camargo CA, Bohlke K, Jick H, Miller RL, Sheikh A | display-authors=etal| title=Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group. | journal=Ann Allergy Asthma Immunol | year= 2006 | volume= 97 | issue= 5 | pages= 596-602 | pmid=17165265 | doi=10.1016/S1081-1206(10)61086-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17165265  }} </ref>
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.  
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].


===Race===
===Race===
*There is no racial predilection to [disease name].
 
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
*There is no racial predilection to [[anaphylaxis]].
 
===Gender===
===Gender===
*[Disease name] affects men and women equally.
 
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
*[[Anaphylaxis]] affects men and women equally with more women being admitted to the hospital for the [[disease]]. <ref name="pmid28800865">{{cite journal| author=LoVerde D, Iweala OI, Eginli A, Krishnaswamy G| title=Anaphylaxis. | journal=Chest | year= 2018 | volume= 153 | issue= 2 | pages= 528-543 | pmid=28800865 | doi=10.1016/j.chest.2017.07.033 | pmc=6026262 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28800865  }} </ref>


===Region===
===Region===
*The majority of [disease name] cases are reported in [geographical region].


*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
*There is no regional predilection to [[anaphylaxis]].


===Developed Countries===
===Developed Countries===
An estimated 1.24% to 16.8% of the population of the United States is considered "at risk" for having an anaphylactic reaction if they are exposed to one or more allergens, especially [[penicillin]] and insect stings. Most of these people successfully avoid their [[allergen]]s and will never experience anaphylaxis.  Of those people who actually experience anaphylaxis, up to 1% may die as a result.<ref>Neugut, Alfred, Anita Ghatak and Rachel Miller. "Anaphylaxis in the United States: An Investigation Into Its Epidemiology." Arch Intern Med. 161.108 January 2001 15-21. 29 January 2007 <http://archinte.ama-assn.org/cgi/content/full/161/1/15>.</ref>  Anaphylaxis results in fewer than 1,000 deaths per year in the U.S. (compared to 2.4 million deaths from all causes each year in the U.S.<ref name="urlFASTSTATS - Deaths and Mortality">{{cite web |url=http://www.cdc.gov/nchs/fastats/deaths.htm |title=FASTSTATS - Deaths and Mortality |format= |work= |accessdate=2013-02-13}}</ref>).  The most common presentation includes sudden cardiovascular collapse (88% of reported cases of severe anaphylaxis).
An estimated 1.24% to 16.8% of the United States population is considered at risk for developing anaphylaxis if they are exposed to one or more [[Allergen|allergens]].  
 
[[Anaphylaxis]] results in fewer than 1,000 deaths per year in the U.S and the most common presentation is [[cardiovascular collapse]] <ref> Neugut, Alfred, Anita Ghatak and Rachel Miller. "Anaphylaxis in the United States: An Investigation Into Its Epidemiology." Arch Intern Med. 161.108 January 2001 15-21. 29 January 2007 <http://archinte.ama-assn.org/cgi/content/full/161/1/15>.</ref>  <ref name="urlFASTSTATS - Deaths and Mortality">{{cite web |url=http://www.cdc.gov/nchs/fastats/deaths.htm |title=FASTSTATS - Deaths and Mortality |format= |work= |accessdate=2013-02-13}}</ref>
===Developing Countries===


==References==
==References==

Latest revision as of 09:43, 15 April 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Dushka Riaz, MD

Epidemiology and Demographics

Prevalence

  • In 2006, the lifetime prevalence of Anaphylaxis was estimated to be 0.05% to 2% in the United States. However it is believed that this is an underestimation because the disease is underdiagnosed. [1]

Case-fatality rate/Mortality rate

Age

  • Patients of all age groups may develop anaphylaxis, however, children and adolescents account for the majority of cases.[3]

Race

Gender

  • Anaphylaxis affects men and women equally with more women being admitted to the hospital for the disease. [1]

Region

Developed Countries

An estimated 1.24% to 16.8% of the United States population is considered at risk for developing anaphylaxis if they are exposed to one or more allergens. Anaphylaxis results in fewer than 1,000 deaths per year in the U.S and the most common presentation is cardiovascular collapse [4] [5]

References

  1. 1.0 1.1 LoVerde D, Iweala OI, Eginli A, Krishnaswamy G (2018). "Anaphylaxis". Chest. 153 (2): 528–543. doi:10.1016/j.chest.2017.07.033. PMC 6026262. PMID 28800865.
  2. Ma L, Danoff TM, Borish L (2014). "Case fatality and population mortality associated with anaphylaxis in the United States". J Allergy Clin Immunol. 133 (4): 1075–83. doi:10.1016/j.jaci.2013.10.029. PMC 3972293. PMID 24332862.
  3. Lieberman P, Camargo CA, Bohlke K, Jick H, Miller RL, Sheikh A; et al. (2006). "Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group". Ann Allergy Asthma Immunol. 97 (5): 596–602. doi:10.1016/S1081-1206(10)61086-1. PMID 17165265.
  4. Neugut, Alfred, Anita Ghatak and Rachel Miller. "Anaphylaxis in the United States: An Investigation Into Its Epidemiology." Arch Intern Med. 161.108 January 2001 15-21. 29 January 2007 <http://archinte.ama-assn.org/cgi/content/full/161/1/15>.
  5. "FASTSTATS - Deaths and Mortality". Retrieved 2013-02-13.

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