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==Overview==
==Overview==
Medical treatment of analgesic nephropathy may include: discontinuation of analgesics, adequate hydration with normal saline and treatment of infections with antibiotics.
Medical treatment of analgesic nephropathy may include: discontinuation of [[Analgesic|analgesics]], adequate hydration with normal [[Saline (medicine)|saline]] and treatment of [[Infection|infections]] with [[Antibiotic|antibiotics]].


==Medical Therapy==
==Medical Therapy==
<s>Treatment of analgesic nephropathy begins with the discontinuation of analgesics, which often halts the progression of the disease and may even result in normalization of kidney function.<ref name="pmid4638849">{{cite journal |author=Linton AL |title=Renal disease due to analgesics. I. Recognition of the problem of analgesic nephropathy |journal=Can Med Assoc J |volume=107 |issue=8 |pages=749–51 |year=1972 |month=October |pmid=4638849 |pmc=1941002 |doi= |url=}}</ref>
After this depending on the damage to kidneys done, kidney transplant or kidney dialysis may be required.An appropriate diet and lifestyle changes may be required.</s>
Medical treatment of analgesic nephropathy may include:<ref name="pmid7002190">{{cite journal| author=Nanra RS| title=Clinical and pathological aspects of analgesic nephropathy. | journal=Br J Clin Pharmacol | year= 1980 | volume= 10 Suppl 2 | issue=  | pages= 359S-368S | pmid=7002190 | doi=10.1111/j.1365-2125.1980.tb01824.x | pmc=1430193 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7002190  }} </ref><ref name="pmid31082145">{{cite journal| author=| title=StatPearls | journal= | year= 2020 | volume=  | issue=  | pages=  | pmid=31082145 | doi= | pmc= | url= }} </ref>
Medical treatment of analgesic nephropathy may include:<ref name="pmid7002190">{{cite journal| author=Nanra RS| title=Clinical and pathological aspects of analgesic nephropathy. | journal=Br J Clin Pharmacol | year= 1980 | volume= 10 Suppl 2 | issue=  | pages= 359S-368S | pmid=7002190 | doi=10.1111/j.1365-2125.1980.tb01824.x | pmc=1430193 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7002190  }} </ref><ref name="pmid31082145">{{cite journal| author=| title=StatPearls | journal= | year= 2020 | volume=  | issue=  | pages=  | pmid=31082145 | doi= | pmc= | url= }} </ref>


* Discontinuation of analgesics:
* Discontinuation of [[Analgesic|analgesics]]:
** Prevents further damage and renal function may recover to normal level
** Prevents further damage and renal function may recover to normal level
* Adequate hydration with normal saline:
* Adequate hydration with normal [[Saline (medicine)|saline]]:
** Correction of volume depletion
** Correction of volume depletion
* Treatment of infections with antibiotics:
* Treatment of [[Infection|infections]] with [[Antibiotic|antibiotics]]:
** Prevents further deterioration
** Prevents further deterioration
* Correction of electrolyte disturbances and systemic acidosis
* Correction of [[Electrolyte disturbance|electrolyte disturbances]] and systemic [[acidosis]]
* Control of severe hypertension
* Control of severe [[hypertension]]


<br />
==References==
==References==



Latest revision as of 06:25, 8 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2], Soumya Sachdeva

Overview

Medical treatment of analgesic nephropathy may include: discontinuation of analgesics, adequate hydration with normal saline and treatment of infections with antibiotics.

Medical Therapy

Medical treatment of analgesic nephropathy may include:[1][2]

References

  1. Nanra RS (1980). "Clinical and pathological aspects of analgesic nephropathy". Br J Clin Pharmacol. 10 Suppl 2: 359S–368S. doi:10.1111/j.1365-2125.1980.tb01824.x. PMC 1430193. PMID 7002190.
  2. "StatPearls". 2020. PMID 31082145.

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