Analgesic nephropathy history and symptoms: Difference between revisions
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{{Analgesic nephropathy}} | {{Analgesic nephropathy}} | ||
{{CMG}} {{AE}} {{SHA}} | {{CMG}} {{AE}} {{SHA}} | ||
==Overview== | ==Overview== | ||
Common findings in patients with analgesic nephropathy include: [[headache]], upper gastrointestinal disease (such as [[peptic ulcer]]), [[anemia]], [[Urinary tract infection|urinary tract infections]], [[pyuria]] and [[hypertension]]. | Common findings in patients with analgesic nephropathy include: [[headache]], upper gastrointestinal disease (such as [[peptic ulcer]]), [[anemia]], [[Urinary tract infection|urinary tract infections]], [[pyuria]] and [[hypertension]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
History, symptoms and and clinical findings in patients with analgesic nephropathy includes:<ref name="pmid7002190">{{cite journal| author=Nanra RS| title=Clinical and pathological aspects of analgesic nephropathy. | journal=Br J Clin Pharmacol | year= 1980 | volume= 10 Suppl 2 | issue= | pages= 359S-368S | pmid=7002190 | doi=10.1111/j.1365-2125.1980.tb01824.x | pmc=1430193 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7002190 }} </ref><ref name="pmid362034">{{cite journal| author=Nanra RS, Stuart-Taylor J, de Leon AH, White KH| title=Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia | History, symptoms and and clinical findings in patients with analgesic nephropathy includes:<ref name="pmid7002190">{{cite journal| author=Nanra RS| title=Clinical and pathological aspects of analgesic nephropathy. | journal=Br J Clin Pharmacol | year= 1980 | volume= 10 Suppl 2 | issue= | pages= 359S-368S | pmid=7002190 | doi=10.1111/j.1365-2125.1980.tb01824.x | pmc=1430193 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7002190 }} </ref><ref name="pmid362034">{{cite journal |author=Nanra RS, Stuart-Taylor J, de Leon AH, White KH |title=Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia |journal=Kidney Int. |volume=13 |issue=1 |pages=79–92 |year=1978 |month=January |pmid=362034 |doi= |url=}}</ref> | ||
* [[Headache]] | * [[Headache]] | ||
| Line 48: | Line 17: | ||
* Tubular epithelial celluria | * Tubular epithelial celluria | ||
* Microscopic [[hematuria]] (35%) | * Microscopic [[hematuria]] (35%) | ||
* Significant [[proteinuria]] (greater than 0.3 gr daily (40%) | * Significant [[proteinuria]] (greater than 0.3 gr daily) (40%) | ||
* [[Transitional cell carcinoma|Transitional cell tumours]] of the [[urothelium]] (in abuse of [[Analgesic|analgesics]] containing [[phenacetin]]) | * [[Transitional cell carcinoma|Transitional cell tumours]] of the [[urothelium]] (in abuse of [[Analgesic|analgesics]] containing [[phenacetin]]) | ||
* Varying degrees of [[Renal insufficiency|renal failure]] (over 85%) | * Varying degrees of [[Renal insufficiency|renal failure]] (over 85%) | ||
Latest revision as of 06:23, 8 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
Common findings in patients with analgesic nephropathy include: headache, upper gastrointestinal disease (such as peptic ulcer), anemia, urinary tract infections, pyuria and hypertension.
History and Symptoms
History, symptoms and and clinical findings in patients with analgesic nephropathy includes:[1][2]
- Headache
- Upper gastrointestinal disease (such as peptic ulcer)
- Anemia (60%)
- Psychiatric disorder
- Urinary tract infections (15-60%)
- Sterile pyuria (95%)
- Hypertension (15-70%)
- Tubular epithelial celluria
- Microscopic hematuria (35%)
- Significant proteinuria (greater than 0.3 gr daily) (40%)
- Transitional cell tumours of the urothelium (in abuse of analgesics containing phenacetin)
- Varying degrees of renal failure (over 85%)
- Clinical gout (5%)
- Acidosis
- Passage of papillae
- Flank or abdominal pain
References
- ↑ Nanra RS (1980). "Clinical and pathological aspects of analgesic nephropathy". Br J Clin Pharmacol. 10 Suppl 2: 359S–368S. doi:10.1111/j.1365-2125.1980.tb01824.x. PMC 1430193. PMID 7002190.
- ↑ Nanra RS, Stuart-Taylor J, de Leon AH, White KH (1978). "Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia". Kidney Int. 13 (1): 79–92. PMID 362034. Unknown parameter
|month=ignored (help)