Adenocarcinoma of the lung natural history, complications, and prognosis: Difference between revisions

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==Overview==
==Overview==
==Natural History==
*The majority of lung cancers present with advanced disease because the symptoms tend to occur later in the course of the disease<ref>"The Presentation and Diagnosis of Lung Cancer and Mesothelioma." Lunger Cancer: A Multidisciplinary Approach. Ed. Alison Leary. Ames: Blackwell, 2012. 15-21. Print.</ref>
*The patient experiences non-specific symptoms such as [[cough]], [[hemoptysis]], [[dyspnea]]  chest pain, [[dysphonia]], [[dysphagia]], lack of appetite, weight loss, and fatigue from 3 weeks to 3 months before seeking medical attention
*While of duration of symptoms, the tumor cell may double 20 times<ref>"The Presentation and Diagnosis of Lung Cancer and Mesothelioma." Lunger Cancer: A Multidisciplinary Approach. Ed. Alison Leary. Ames: Blackwell, 2012. 15-21. Print.</ref>
*In more advanced disease, the tumor may spread to other organs such as the spinal cord, brain, and bone
*These patients may develop symptoms such as leg weakness [[paresthesias]], bladder/bladder dysfunction, [[seizures]], [[hemiplegia]], cranial nerve palsies, confusion, personality changes, skeletal pain, and/or [[pleuritic]] pain <ref>"The Presentation and Diagnosis of Lung Cancer and Mesothelioma." Lunger Cancer: A Multidisciplinary Approach. Ed. Alison Leary. Ames: Blackwell, 2012. 15-21. Print.</ref>
*Once the cancer spreads to the other organs, it is most likely fatal


==Prognosis==
==Prognosis==

Revision as of 14:03, 22 December 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]

Overview

Natural History

  • The majority of lung cancers present with advanced disease because the symptoms tend to occur later in the course of the disease[1]
  • The patient experiences non-specific symptoms such as cough, hemoptysis, dyspnea chest pain, dysphonia, dysphagia, lack of appetite, weight loss, and fatigue from 3 weeks to 3 months before seeking medical attention
  • While of duration of symptoms, the tumor cell may double 20 times[2]
  • In more advanced disease, the tumor may spread to other organs such as the spinal cord, brain, and bone
  • These patients may develop symptoms such as leg weakness paresthesias, bladder/bladder dysfunction, seizures, hemiplegia, cranial nerve palsies, confusion, personality changes, skeletal pain, and/or pleuritic pain [3]
  • Once the cancer spreads to the other organs, it is most likely fatal


Prognosis

Non–small cell lung cancer survival rate by stage[4]

Stage 5-year survival rate
IA 49%
IB 45%
IIA 30%
IIB 31%
IIIA 14%
IIIB 5%
IV 1%

References

  1. "The Presentation and Diagnosis of Lung Cancer and Mesothelioma." Lunger Cancer: A Multidisciplinary Approach. Ed. Alison Leary. Ames: Blackwell, 2012. 15-21. Print.
  2. "The Presentation and Diagnosis of Lung Cancer and Mesothelioma." Lunger Cancer: A Multidisciplinary Approach. Ed. Alison Leary. Ames: Blackwell, 2012. 15-21. Print.
  3. "The Presentation and Diagnosis of Lung Cancer and Mesothelioma." Lunger Cancer: A Multidisciplinary Approach. Ed. Alison Leary. Ames: Blackwell, 2012. 15-21. Print.
  4. Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/prognosis-and-survival/survival-statistics/?region=ab


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