Acinic cell carcinoma natural history, complications and prognosis
Natural History, Complications & Prognosis
Swathi Venkatesan, M.B.B.S.[1]
- Acinic cell carcinoma is a slow growing tumor [1]
- Tumor may affect the facial nerve or other adjacent tissues depending on its location
- Prognosis is most favorable when the parotid gland is involved
- Progression of acinic cell carcinoma is slow but it may involve adjacent tissues if not treated adequately.
- Acinic cell carcinoma can spread to adjacent organs and eventually be lethal if not intervened on time.
- The prognosis is more favorable when the tumor is in a major salivary gland; the parotid gland is most favorable, followed by the submandibular gland
- The least favorable primary sites are the sublingual and minor salivary glands
- Large bulky tumors or high-grade tumors carry a least favorable or poor prognosis and may best be treated by surgical resection combined with postoperative radiation therapy
- ↑ Al-Zaher, Nabil; Obeid, Amani; Al-Salam, Suhail; Al-Kayyali, Bassam Sulaiman (2009). "Acinic cell carcinoma of the salivary glands: A literature review". Hematology/Oncology and Stem Cell Therapy. 2 (1): 259–264. doi:10.1016/S1658-3876(09)50035-0. ISSN 1658-3876.