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==References==
==References==
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{{Reflist|2}}
[[CME Category::Cardiology]]


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[[Category:Electrophysiology]]
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Latest revision as of 00:26, 15 March 2016

Arrhythmogenic right ventricular dysplasia Microchapters

Home

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Arrhythmogenic right ventricular dysplasia from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

X - Ray

ECG

Cardiac MRI

Echocardiogram

Other Imaging Findings

Endomyocardial biopsy

Atuopsy

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Future or Investigational Therapies

ARVD1 On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of ARVD1

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

National Guidelines Clearinghouse

NICE Guidance

FDA on ARVD1

CDC on ARVD1

ARVD1 in the news

Blogs onARVD1

Directions to Hospitals Treating Arrhythmogenic right ventricular dysplasia

Risk calculators and risk factors for ARVD1

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Arrhythmogenic right ventricular dysplasia type 1;

Overview

Pathophysiology

The pathogenesis of ARVD involves apoptosis with fatty and fibro-fatty infiltration of the right ventricular free wall leading to heart failure and ventricular arrhythmias.

Genetics

There is an autosomal dominant pattern of inheritance. This variant is due to a heterozygous mutation in the TGFB3 gene (190230) on chromosome 14q24.[1]

Epidemiology and Demographics

The incidence of ARVD is about 1/10,000 in the general population in the United States, although some studies have suggested that it may be as common as 1/1,000. It accounts for up to 17% of all sudden cardiac deaths in the young. In Italy, the incidence is 40/10,000, making it the most common cause of sudden cardiac death in the young population. It is more common in Northern Italy.

Gender

The male to female ratio is 3:1.

Natural History, Complications, Prognosis

Diagnosis

Symptoms

Electrocardiogram

Echocardiogram

MRI

References

  1. Rampazzo A, Beffagna G, Nava A et-al. Arrhythmogenic right ventricular cardiomyopathy type 1 (ARVD1): confirmation of locus assignment and mutation screening of four candidate genes. Eur. J. Hum. Genet. 2003;11 (1): 69-76. doi:10.1038/sj.ejhg.5200914 - Pubmed citation

CME Category::Cardiology