ANP32E: Difference between revisions

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

VisualWikitext

Latest revision as of 03:20, 27 October 2017

Acidic leucine-rich nuclear phosphoprotein 32 family member E is a protein that in humans is encoded by the ANP32E gene.^[1]^[2] The ANP32E gene is located on chromosome 1q22.^[1] In mammalian cells, ANP32E has been shown to be an H2A.Z chaperone capable of promoting the removal of H2A.Z from chromatin.^[3] In brain tissue, ANP32E together with Cpd1 regulate protein phosphatase 2A activity at synapses during synaptogenesis^[4] and has been observed to form a complex with ANP32A and SET that stabilizes short-lived mRNAs containing AU-rich elements, as well as having acetyltransferase inhibitory activity (in a complex with SET) and having a role in chromatin remodeling and transcriptional regulation.^[5]

References

↑ ^1.0 ^1.1 Jiang M, Ma Y, Ni X, Cao G, Ji C, Cheng H, Tang R, Xie Y, Mao Y (Nov 2002). "Molecular cloning and characterization of a novel human gene (ANP32E alias LANPL) from human fetal brain". Cytogenet Genome Res. 97 (1–2): 68–71. doi:10.1159/000064058. PMID 12438741.
↑ "Entrez Gene: ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E".
↑ Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C, Hamiche A (2014). "ANP32E is a histone chaperone that removes H2A.Z from chromatin". Nature. 505 (7485): 648–53. doi:10.1038/nature12922. PMID 24463511.
↑ Costanzo RV, Vilá-Ortíz GJ, Perandones C, Carminatti H, Matilla A, Radrizzani M (2006). "Anp32e/Cpd1 regulates protein phosphatase 2A activity at synapses during synaptogenesis". Eur. J. Neurosci. 23 (2): 309–24. doi:10.1111/j.1460-9568.2005.04555.x. PMID 16420440.
↑ Santa-Coloma TA (2003). "Anp32e (Cpd1) and related protein phosphatase 2 inhibitors". Cerebellum. 2 (4): 310–20. doi:10.1080/14734220310017212. PMID 14964690.

External links

Human ANP32E genome location and ANP32E gene details page in the UCSC Genome Browser.

Matilla A, Radrizzani M (2005). "The Anp32 family of proteins containing leucine-rich repeats". Cerebellum. 4 (1): 7–18. doi:10.1080/14734220410019020. PMID 15895553.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[pmid12438741-1] 1.0 ^1.1 Jiang M, Ma Y, Ni X, Cao G, Ji C, Cheng H, Tang R, Xie Y, Mao Y (Nov 2002). "Molecular cloning and characterization of a novel human gene (ANP32E alias LANPL) from human fetal brain". Cytogenet Genome Res. 97 (1–2): 68–71. doi:10.1159/000064058. PMID 12438741.

[entrez-2] "Entrez Gene: ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E".

[pmid24463511-3] Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C, Hamiche A (2014). "ANP32E is a histone chaperone that removes H2A.Z from chromatin". Nature. 505 (7485): 648–53. doi:10.1038/nature12922. PMID 24463511.

[pmid16420440-4] Costanzo RV, Vilá-Ortíz GJ, Perandones C, Carminatti H, Matilla A, Radrizzani M (2006). "Anp32e/Cpd1 regulates protein phosphatase 2A activity at synapses during synaptogenesis". Eur. J. Neurosci. 23 (2): 309–24. doi:10.1111/j.1460-9568.2005.04555.x. PMID 16420440.

[pmid14964690-5] Santa-Coloma TA (2003). "Anp32e (Cpd1) and related protein phosphatase 2 inhibitors". Cerebellum. 2 (4): 310–20. doi:10.1080/14734220310017212. PMID 14964690.

[1]

[2]

[3]

[4]

[5]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Acidic leucine-rich nuclear phosphoprotein 32 family member E''' is a [[protein]] that in humans is encoded by the ''ANP32E'' [[gene]].<ref name="pmid12438741">{{cite journal |vauthors=Jiang M, Ma Y, Ni X, Cao G, Ji C, Cheng H, Tang R, Xie Y, Mao Y | title = Molecular cloning and characterization of a novel human gene (ANP32E alias LANPL) from human fetal brain | journal = Cytogenet Genome Res | volume = 97 | issue = 1–2 | pages = 68–71 |date=Nov 2002 | pmid = 12438741 | pmc =  | doi =10.1159/000064058  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81611| accessdate = }}</ref> The ANP32E gene is located on chromosome 1q22.<ref name="pmid12438741" /> In mammalian cells, ANP32E has been shown to be an [[H2AFZ | H2A.Z]] chaperone capable of promoting the removal of H2A.Z from chromatin.<ref name="pmid24463511">{{cite journal |vauthors=Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C, Hamiche A | title = ANP32E is a histone chaperone that removes H2A.Z from chromatin | journal = Nature | volume = 505 | issue = 7485 | pages = 648–53 | year = 2014 | pmid = 24463511 | doi = 10.1038/nature12922 }}</ref> In brain tissue, ANP32E together with Cpd1 regulate protein phosphatase 2A activity at synapses during synaptogenesis<ref name="pmid16420440">{{cite journal |vauthors=Costanzo RV, Vilá-Ortíz GJ, Perandones C, Carminatti H, Matilla A, Radrizzani M | title = Anp32e/Cpd1 regulates protein phosphatase 2A activity at synapses during synaptogenesis | journal = Eur. J. Neurosci. | volume = 23 | issue = 2 | pages = 309–24 | year = 2006 | pmid = 16420440 | doi = 10.1111/j.1460-9568.2005.04555.x }}</ref> and has been observed to form a complex with ANP32A and SET that stabilizes short-lived mRNAs containing AU-rich elements, as well as having acetyltransferase inhibitory activity (in a complex with SET) and having a role in chromatin remodeling and transcriptional regulation.<ref name="pmid14964690">{{cite journal | author = Santa-Coloma TA | title = Anp32e (Cpd1) and related protein phosphatase 2 inhibitors | journal = Cerebellum | volume = 2 | issue = 4 | pages = 310–20 | year = 2003 | pmid = 14964690 | doi = 10.1080/14734220310017212 }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+==See also==
-{{GNF_Protein_box
+* [[ANP32A]], [[ANP32B]], [[ANP32C]], [[ANP32D]]
- | image =
- | image_source =
- | PDB =
- | Name = Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
- | HGNCid = 16673
- | Symbol = ANP32E
- | AltSymbols =; LANP-L; LANPL; MGC5350
- | OMIM = 609611
- | ECnumber =
- | Homologene = 41519
- | MGIid = 1913721
- | GeneAtlas_image1 = PBB_GE_ANP32E_208103_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_ANP32E_221505_at_tn.png
- | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0019212 |text = phosphatase inhibitor activity}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0016023 |text = cytoplasmic membrane-bound vesicle}}
- | Process =
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 81611
-    | Hs_Ensembl = ENSG00000143401
-    | Hs_RefseqProtein = NP_112182
-    | Hs_RefseqmRNA = NM_030920
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 1
-    | Hs_GenLoc_start = 148457341
-    | Hs_GenLoc_end = 148475130
-    | Hs_Uniprot = Q9BTT0
-    | Mm_EntrezGene = 66471
-    | Mm_Ensembl = ENSMUSG00000015749
-    | Mm_RefseqmRNA = NM_023210
-    | Mm_RefseqProtein = NP_075699
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 3
-    | Mm_GenLoc_start = 96014696
-    | Mm_GenLoc_end = 96032381
-    | Mm_Uniprot = Q3TX26
-  }}
-}}
-'''Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E''', also known as '''ANP32E''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81611| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+==References==
-{{PBB_Summary
+{{reflist}}
-| section_title =
-| summary_text =
+==External links==
-}}
+* {{UCSC gene info|ANP32E}}
-==References==
-{{reflist|2}}
 ==Further reading==
 {{refbegin | 2}}
-{{PBB_Further_reading
+*{{cite journal  |vauthors=Matilla A, Radrizzani M |title=The Anp32 family of proteins containing leucine-rich repeats |journal=Cerebellum |volume=4 |issue= 1 |pages= 7–18 |year= 2005 |pmid= 15895553 |doi=10.1080/14734220410019020  }}
-| citations =
+*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | author=Matilla A, Radrizzani M |title=The Anp32 family of proteins containing leucine-rich repeats. |journal=Cerebellum |volume=4 |issue= 1 |pages= 7-18 |year= 2005 |pmid= 15895553 |doi=  }}
+*{{cite journal  |vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948  }}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal |vauthors=Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M | title = Nucleolar proteome dynamics | journal = Nature | volume = 433 | issue = 7021 | pages = 77–83 | year = 2005 | pmid = 15635413 | doi = 10.1038/nature03207 }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
-*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
-*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
-*{{cite journal  | author=Jiang M, Ma Y, Ni X, ''et al.'' |title=Molecular cloning and characterization of a novel human gene (ANP32E alias LANPL) from human fetal brain. |journal=Cytogenet. Genome Res. |volume=97 |issue= 1-2 |pages= 68-71 |year= 2003 |pmid= 12438741 |doi=  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
-*{{cite journal  | author=Andersen JS, Lam YW, Leung AK, ''et al.'' |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77-83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }}
-*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
-}}
 {{refend}}
+{{gene-1-stub}}
-{{protein-stub}}
-{{WikiDoc Sources}}

ANP32E: Difference between revisions

Latest revision as of 03:20, 27 October 2017

Contents

See also

References

External links

Further reading

Navigation menu