AHA/ASA guideline recommendations for prevention of stroke: Difference between revisions

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|colspan="1" style="text-align:center; background:LightCoral"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class III]] (Harm)
|colspan="1" style="text-align:center; background:LightCoral"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class III]] (Harm)
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|bgcolor="LightCoral"|<nowiki>"</nowiki>'''1.''' Genetic screening of the general population for prevention of a first stroke is not recommended ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
|bgcolor="LightCoral"|<nowiki>"</nowiki>'''1.'''Genetic screening to determine risk for [[myopathy]] is not recommended when initiation of [[statin]] therapy is being considered ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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|bgcolor="LightCoral"|<nowiki>"</nowiki>'''2.''' Screening of patients at risk for myopathy in the setting of statin use is not recommended when considering initiation of [[statin]] therapy at this time''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
|bgcolor="LightCoral"|<nowiki>"</nowiki>'''2.''' Genetic screening of the general population for the prevention of a first stroke is not recommended ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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|bgcolor="LightCoral"|<nowiki>"</nowiki>'''4.'''Universal screening for intracranial aneurysms in carriers of mutations for Mendelian disorders associated with [[aneurysm]] is not recommended ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
|bgcolor="LightCoral"|<nowiki>"</nowiki>'''3.'''Screening for intracranial aneurysms in every car- rier of [[autosomal-dominant polycystic kidney disease]] or [[Ehlers-Danlos|Ehlers-Danlos type IV mutations]] is not recommended ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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|bgcolor="LightCoral"|<nowiki>"</nowiki>'''5.''' Dosing with [[vitamin K antagonists]] on the basis of [[pharmacogenetics]] is not recommended at this time''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
|bgcolor="LightCoral"|<nowiki>"</nowiki>'''4.''' Noninvasive screening for unruptured intracranial aneurysms in patients with no more than 1 relative with [[SAH]] or intracranial aneurysms is not recommended ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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|bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''5.''' Noninvasive screening for unruptured intracranial aneurysms in patients with cervical [[fibromuscular dysplasia]] may be considered''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
|bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''5.''' Noninvasive screening for unruptured intracranial aneurysms in patients with cervical [[fibromuscular dysplasia]] may be considered''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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|bgcolor="LightCoral"|<nowiki>"</nowiki>'''6.''' harmacogenetic dosing of vitamin K antagonists may be considered when therapy is initiated''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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Revision as of 20:29, 17 November 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];

2014 AHA/ASA Guidelines for the Primary Prevention of Stroke[1]

Genetic Factors: Recommendations

Class III (Harm)
"1.Genetic screening to determine risk for myopathy is not recommended when initiation of statin therapy is being considered (Level of Evidence: C)"
"2. Genetic screening of the general population for the prevention of a first stroke is not recommended (Level of Evidence: C)"
"3.Screening for intracranial aneurysms in every car- rier of autosomal-dominant polycystic kidney disease or Ehlers-Danlos type IV mutations is not recommended (Level of Evidence: C)"
"4. Noninvasive screening for unruptured intracranial aneurysms in patients with no more than 1 relative with SAH or intracranial aneurysms is not recommended (Level of Evidence: C)"
Class IIa
"1. Obtaining a family history can be useful to help identify persons who may be at increased risk of stroke (Level of Evidence: A)"
Class IIb
"1. Referral for genetic counseling may be considered for patients with rare genetic causes of stroke (Level of Evidence: C)"
"2. Treatment for certain genetic conditions that pre- dispose to stroke (eg, Fabry disease and enzyme replacement therapy) might be reasonable but has not been shown to reduce risk of stroke, and its effectiveness is unknown (Level of Evidence: C)"
"3. Noninvasive screening for unruptured intracranial aneurysms in patients with ADPKD and ≥1 relatives with ADPKD and SAH or intracranial aneurysm may be considered(Level of Evidence: C)"
"4. Noninvasive screening for unruptured intracranial aneurysms in patients with ≥2 first-degree relatives with SAH or intracranial aneurysms might be reasonable (Level of Evidence: C)"
"5. Noninvasive screening for unruptured intracranial aneurysms in patients with cervical fibromuscular dysplasia may be considered(Level of Evidence: C)"
"6. harmacogenetic dosing of vitamin K antagonists may be considered when therapy is initiated(Level of Evidence: C)"

References

  1. 2014 AHA/ASA Guidelines for the Primary Prevention of Stroke http://stroke.ahajournals.org/content/early/2014/10/28/STR.00000000000000467 Accessed on November 17, 2016


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