(RNA-polymerase)-subunit kinase: Difference between revisions
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===Gene Ontology (GO) codes=== | ===Gene Ontology (GO) codes=== | ||
{{GO code links | GO_code=0008353 | name=RNA polymerase subunit kinase}} | {{GO code links | GO_code=0008353 | name=RNA polymerase subunit kinase}} | ||
[[Category:EC 2.7.11]] | [[Category:EC 2.7.11]] | ||
[[Category:Enzymes of unknown structure]] | [[Category:Enzymes of unknown structure]] | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 20:39, 18 May 2009
In enzymology, a RNA-polymerase-subunit kinase (EC 2.7.11.23) is an enzyme that catalyzes the chemical reaction
- ATP + [DNA-directed RNA polymerase] <math>\rightleftharpoons</math> ADP + phospho- [DNA-directed RNA polymerase]
Thus, the two substrates of this enzyme are ATP and [DNA-directed RNA polymerase], whereas its two products are ADP and phospho- [DNA-directed RNA polymerase].
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[DNA-directed RNA polymerase] phosphotransferase. Other names in common use include CTD kinase, and STK9.
References
- Lee JM, Greenleaf AL (1989). "A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II". Proc. Natl. Acad. Sci. U. S. A. 86: 3624&ndash, 8. PMID 2657724.
External links
- The CAS registry number for this enzyme class is Template:CAS registry.