Tuberculosis classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The current clinical classification system for tuberculosis (TB) is based on the pathogenesis of the disease.

Classification

Health care providers should comply with local laws and regulations requiring the reporting of TB. All persons with class 3 or class 5 TB should be reported promptly to the local health department.

Classification System for TB
Class Type Description
0 No TB exposure
Not infected
No history of exposure
Negative reaction to tuberculin skin test
1 TB exposure
No evidence of infection
History of exposure
Negative reaction to tuberculin skin test
2 TB infection
No disease
Positive reaction to tuberculin skin test
Negative bacteriologic studies (if done)
No clinical, bacteriologic, or radiographic evidence of TB
3 TB, clinically active M. tuberculosis cultured (if done)
Clinical, bacteriologic, or radiographic evidence of current disease
4 TB
Not clinically active
History of episode(s) of TB
or
Abnormal but stable radiographic findings
Positive reaction to the tuberculin skin test
Negative bacteriologic studies (if done)
and
No clinical or radiographic evidence of current disease
5 TB suspect Diagnosis pending
TB disease should be ruled in or out within 3 months

CDC TB Classification for Immigrants and Refugees

The U.S. Citizenship and Immigration Services has an additional TB classification for immigrants and refugees developed by the Centers for Disease Control and Prevention (CDC). The 'B Notification Program' is an important screening strategy to identify new arrivals who have a high risk for TB.

United States Immigrant/Refugee TB Classification
Class Chest X-ray AFB smear Restrictions
A - TB, infectious Active TB Positive No entry to U.S. until treated and smears are negative
B1 - TB, clinically active, not infectious Active TB Negative Report to local health department for further medical evaluation within 30 days of arrival in U.S.
B2 - TB, not clinically active Inactive TB Not required unless symptomatic Same as above
No class (Normal) Normal Not required None

Class B3 (TB, old or healed; chest X-ray with calcification) has been omitted from the classification scheme because it has not been found to be associated with active TB.

See list of notifiable diseases.

References

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