Indigestion classification

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Indigestion

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Classification

Dyspepsia is broadly classified into two major types:

  • Ulcer dyspepsia - accounts to 20-30 % of all dyspepsia cases and is caused by Peptic ulcer disease, GERD. Structural disease of the gastrointestinal tract exists in ulcer dyspepsia and hence endoscopy is abnormal.
  • Non-ulcer dyspepsia - also called Functional dyspepsia. Functional dyspepsia (FD) is defined by the Rome III criteria as symptoms of epigastric pain or discomfort (prevalence in FD of 89-90%), postprandial fullness (75-88%), and early satiety (50-82%) within the last 3 months with symptom onset at least 6 months earlier. Patients cannot have any evidence of structural disease to explain symptoms and predominant symptoms of gastroesophageal reflux are exclusionary.[1] Causes of functional dyspepsia are not clear but researchers have focused on the following factors:
    • Gastric motor function
    • Visceral sensitivity
    • Helicobacter pylori infection
    • Psychosocial factors

References

  1. Lacy BE, Talley NJ, Locke GR; et al. (2012). "Review article: current treatment options and management of functional dyspepsia". Aliment. Pharmacol. Ther. 36 (1): 3–15. doi:10.1111/j.1365-2036.2012.05128.x. PMID 22591037. Unknown parameter |month= ignored (help)