MED12

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Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)
Identifiers
Symbols MED12 ; OPA1; CAGH45; HOPA; KIAA0192; TNRC11; TRAP230
External IDs Template:OMIM5 Template:MGI HomoloGene68441
RNA expression pattern
File:PBB GE MED12 203506 s at tn.png
File:PBB GE MED12 211342 x at tn.png
File:PBB GE MED12 216071 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae), also known as MED12, is a human gene.[1]


References

  1. "Entrez Gene: MED12 mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)".

Further reading

  • Fondell JD, Ge H, Roeder RG (1996). "Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex". Proc. Natl. Acad. Sci. U.S.A. 93 (16): 8329–33. PMID 8710870.
  • Nagase T, Seki N, Ishikawa K; et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 3 (1): 17–24. PMID 8724849.
  • Yamagata K, Takeda J, Menzel S; et al. (1996). "Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle". Diabetologia. 39 (6): 725–30. PMID 8781769.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.
  • Margolis RL, Abraham MR, Gatchell SB; et al. (1997). "cDNAs with long CAG trinucleotide repeats from human brain". Hum. Genet. 100 (1): 114–22. PMID 9225980.
  • Philibert RA, King BH, Winfield S; et al. (1998). "Association of an X-chromosome dodecamer insertional variant allele with mental retardation". Mol. Psychiatry. 3 (4): 303–9. PMID 9702738.
  • Ito M, Yuan CX, Malik S; et al. (1999). "Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators". Mol. Cell. 3 (3): 361–70. PMID 10198638.
  • Rachez C, Lemon BD, Suldan Z; et al. (1999). "Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex". Nature. 398 (6730): 824–8. doi:10.1038/19783. PMID 10235266.
  • Näär AM, Beaurang PA, Zhou S; et al. (1999). "Composite co-activator ARC mediates chromatin-directed transcriptional activation". Nature. 398 (6730): 828–32. doi:10.1038/19789. PMID 10235267.
  • Philibert RA, Winfield SL, Damschroder-Williams P; et al. (1999). "The genomic structure and developmental expression patterns of the human OPA-containing gene (HOPA)". Hum. Genet. 105 (1–2): 174–8. PMID 10480376.
  • Joensuu T, Hämäläinen R, Yuan B; et al. (2001). "Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3". Am. J. Hum. Genet. 69 (4): 673–84. PMID 11524702.
  • Beyer KS, Klauck SM, Benner A; et al. (2002). "Association studies of the HOPA dodecamer duplication variant in different subtypes of autism". Am. J. Med. Genet. 114 (1): 110–5. PMID 11840515.
  • Tchernev VT, Mansfield TA, Giot L; et al. (2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Mol. Med. 8 (1): 56–64. PMID 11984006.
  • Ge K, Guermah M, Yuan CX; et al. (2002). "Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. doi:10.1038/417563a. PMID 12037571.
  • Zhou R, Bonneaud N, Yuan CX; et al. (2002). "SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex". Nucleic Acids Res. 30 (14): 3245–52. PMID 12136106.
  • Wang Q, Sharma D, Ren Y, Fondell JD (2003). "A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression". J. Biol. Chem. 277 (45): 42852–8. doi:10.1074/jbc.M206061200. PMID 12218053.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Sato S, Tomomori-Sato C, Banks CA; et al. (2003). "Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3". J. Biol. Chem. 278 (17): 15123–7. doi:10.1074/jbc.C300054200. PMID 12584197.
  • Gwack Y, Baek HJ, Nakamura H; et al. (2003). "Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation". Mol. Cell. Biol. 23 (6): 2055–67. PMID 12612078.
  • Kitano T, Schwarz C, Nickel B, Pääbo S (2004). "Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees". Mol. Biol. Evol. 20 (8): 1281–9. doi:10.1093/molbev/msg134. PMID 12777533.

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