Multiple sclerosis medical therapy

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Bladder

Treatment objectives are aliviation of symptoms of urinary dysfunction, treatment of urinary infections, reduction of complicating factors and preservation of renal function.Treatments can be classified in two main subtypes: pharmacological and non pharmacological.

Pharmacological treatments vary greatly depending on the origin or type of dysfunction; however some examples of the medications used are:[1] alfuzosin for retention,[2] trospium and flavoxate for urgency and incontinency,[3][4] or desmopressin for nocturia.[5][6]

Non pharmacological treatments involve the use of pelvic floor muscle training, stimulation, biofeedback,pessaries, bladder retraining, and sometimes intermittent catheterization.[7]

  1. Ayuso-Peralta L, de Andrés C (2002). "[Symptomatic treatment of multiple sclerosis]". Revista de neurologia (in Spanish; Castilian). 35 (12): 1141–53. PMID 12497297.
  2. Information from the USA National library of medicine on alfuzosin[1]
  3. Information from the USA National library of medicine on trospium[2]
  4. Information from the USA National library of medicine on flavoxate [3]
  5. Bosma R, Wynia K, Havlíková E, De Keyser J, Middel B (2005). "Efficacy of desmopressin in patients with multiple sclerosis suffering from bladder dysfunction: a meta-analysis". Acta Neurol. Scand. 112 (1): 1–5. doi:10.1111/j.1600-0404.2005.00431.x. PMID 15932348.
  6. Information from the USA National library of medicine on desmopressin[4]
  7. Frances M Diro (2006) "Urological Management in Neurological Disease". [5]