Gs alpha subunit

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GNAS complex locus
Identifiers
SymbolGNAS
Alt. symbolsGNAS1
Entrez2778
HUGO4392
OMIM139320
RefSeqNM_000516
UniProtQ5JWF2
Other data
LocusChr. 20 q13.2-13.3


Overview

The Gs alpha subunit (or Gs protein) is a heterotrimeric G protein subunit which activates adenylate cyclase.

Receptors

The G-protein coupled receptors that couple to this kind of G-protein are for example:

Function

The general function of Gs is to activate adenylate cyclase, which, in turn, produces cAMP, which, in turn activates cAMP-dependent protein kinase. Further effects of Gs is thus found in function of cAMP-dependent protein kinase.

See also

External links

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