Amodiaquine

Amodiaquine

File:Amodiaquine.svg
Clinical data
ATC code	P01BA06 (WHO)
Pharmacokinetic data
Elimination half-life	5.2 ± 1.7 (range 0.4 to 5.5) minutes
Identifiers
IUPAC name 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol
CAS Number	86-42-0
PubChem CID	2165
DrugBank	APRD00796
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C20H22ClN3O
Molar mass	355.861 g/mol

Amodiaquine (trade names Camoquin, Flavoquine) is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.

Amodiaquine has been shown to be more effective than chloroquine in treating CRPF (chloroquine-resistant Plasmodium falciparum) malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine, like chloroquine, is generally well tolerated. Although licensed, this drug is not marketed in the United States but is widely available in Africa. Its use, therefore, is probably more practicable in long-term visitors and persons who will reside in Africa.

Notes

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